SCHEMBL3286343

SCHEMBL3286343

Cc1cc(C)c(N=Nc2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HSP90AA1 P07900 1/20 0.48
ATM Q13315 1/20 0.48
RAPGEF4 Q8WZA2 5/20 0.43
MAPT P10636 3/20 0.36
ALDH1A1 P00352 3/20 0.36
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.36
TSHR P16473 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3286340 1.00 MEN1 (0.48) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL3933025 0.87 MEN1 (0.68) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL1405485 0.87 MEN1 (0.68) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL27621238 0.83 F2 (0.38) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL3285227 0.81 ALDH1A1 (0.52) MEN1KMT2AHSP90AA1ATMMAPT
SCHEMBL3285225 0.81 ALDH1A1 (0.52) MEN1KMT2AHSP90AA1ATMMAPT
SCHEMBL502928 0.80 RAPGEF4 (0.43) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL6377762 0.78 RAPGEF4 (0.41) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL2584959 0.77 RAPGEF4 (0.48) RAPGEF4MAPTALDH1A1NPC1RAB9A
SCHEMBL2586606 0.77 RAPGEF4 (0.48) RAPGEF4MAPTALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3355120-B1 TONER AND IMAGE FORMATION METHOD KONICA MINOLTA INC (JP) 2022-01-26 EP disclosed
US-9404001-B2 Photochromic latex ink XEROX CORPORATION (US) 2016-08-02 US disclosed
US-20150153479-A1 PHOTOCHROMIC LATEX INK XEROX CORPORATION (US) 2015-06-04 US disclosed
US-7708396-B2 Photochromic phase change inks XEROX CORPORATION (US) 2010-05-04 US disclosed
US-20070211124-A1 PHOTOCHROMIC PHASE CHANGE INKS XEROX CORPORATION (US) 2007-09-13 US disclosed
US-5759729-A A DRY TONER COMPRISING A RESIN, PHOTOCHROMATIC SPIROPYRAN, -OXAZINE OR -THIOPYRAN DYE AND A CHARGE CONTROL AGENT;ELECTROGRAPHY; XEROGRAPHY XEROX CORPORATION (US) 1998-06-02 US disclosed
US-5710420-A Method for embedding and recovering machine-readable information XEROX CORPORATION (US) 1998-01-20 US disclosed
US-5633109-A Ink compositions with liposomes containing photochromic compounds XEROX CORPORATION (US) 1997-05-27 US disclosed
US-5593486-A Photochromic hot melt ink compositions XEROX CORPORATION (US) 1997-01-14 US disclosed
US-5551973-A LIQUID CRYSTAL GEL PHASE, MICROEMULSION PHASE XEROX CORPORATION (US) 1996-09-03 US disclosed