Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.44 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505467 | 0.74 | TRIM24 (0.54) | ALDH1A1TRIM24TRIM33GAAATM | |
| SCHEMBL11327402 | 0.72 | TRIM24 (0.44) | ALDH1A1TRIM24TRIM33GAAATM | |
| SCHEMBL3996663 | 0.71 | TRIM24 (0.47) | ALDH1A1TRIM24TRIM33GAAATM | |
| SCHEMBL11877985 | 0.68 | TRIM24 (0.40) | ALDH1A1TRIM24TRIM33ATMKMT2A | |
| SCHEMBL9577633 | 0.68 | MEN1 (0.31) | PKMKMT2A | |
| SCHEMBL29277391 | 0.67 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL11871896 | 0.67 | TRIM24 (0.39) | ALDH1A1TRIM24TRIM33ATMKMT2A | |
| SCHEMBL11880901 | 0.67 | TRIM24 (0.42) | ALDH1A1TRIM24TRIM33GAAATM | |
| SCHEMBL11555051 | 0.67 | TRIM24 (0.46) | ALDH1A1TRIM24TRIM33GAAATM | |
| SCHEMBL5403668 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705038-B2 | Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives | INTERVET, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| EP-1811841-B1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF PARASITICIDAL 2-PHENYL-3-(1H-PYRROL-2-YL) ACRYLONITRILE DERIVATIVES | SCHERING PLOUGH LTD (CH) | 2009-10-28 | — | — | EP | disclosed |
| EP-1811841-A2 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF PARASITICIDAL 2-PHENYL-3-(1H-PYRROL-2-YL) ACRYLONITRILE DERIVATIVES | Schering-Plough Ltd. (CH) | 2007-08-01 | — | — | EP | disclosed |
| US-20060128779-A1 | Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION | 2006-06-15 | — | — | US | disclosed |
| WO-2006055565-A2 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF PARASITICIDAL 2-PHENYL-3-(1H-PYRROL-2-YL) ACRYLONITRILE DERIVATIVES | SCHERING-PLOUGH LTD. (CH) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128779-A1 | Control of parasites in animals by the use of parasiticidal 2-phenyl-3-(1H-pyrrol-2-yl)acrylonitrile derivatives | PNN, AADAC, EPX | ALDH1A1 504/4885TRIM24 4480/4885TRIM33 1839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.