Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 1.00 |
| ▸ | AKT2 | P31751 | 6/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 2/20 | 1.00 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.97 |
| ▸ | TP53 | P04637 | 1/20 | 0.97 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.71 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.71 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.71 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.71 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | AURKA | O14965 | 2/20 | 0.62 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.62 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.62 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.62 |
| ▸ | AKT1 | P31749 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9095854 | 0.98 | HTT (1.00) | HTTAKT2LMNAALOX15MAP3K5 | |
| SCHEMBL6755685 | 0.91 | HTT (0.86) | HTTAKT2LMNAALOX15MAP3K5 | |
| SCHEMBL29898244 | 0.91 | HTT (0.86) | HTTAKT2LMNAALOX15MAP3K5 | |
| SCHEMBL12048138 | 0.91 | HTT (0.86) | HTTAKT2LMNAALOX15MAP3K5 | |
| SCHEMBL1030420 | 0.85 | HTT (0.76) | HTTAKT2LMNAALOX15MAP3K5 | |
| SCHEMBL336613 | 0.83 | MAPK1 (1.00) | HTTAKT2LMNAALOX15MAP3K5 | |
| SCHEMBL31713036 | 0.81 | PTK2B (1.00) | HTTAKT2LMNAALOX15MAP3K5 | |
| SCHEMBL12048165 | 0.81 | HTT (0.69) | HTTAKT2LMNAALOX15MAP3K5 | |
| Hydrochloric Acid SCHEMBL5219673 | 0.80 | AKT2 (0.97) | HTTAKT2LMNAALOX15MAP3K5 | |
| SCHEMBL2301186 | 0.80 | HTT (0.75) | HTTAKT2LMNAALOX15MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119855813-A | Pyridazinone-derived compounds for modulating MYC and for medical use | 遗传智力公司 | 2025-04-18 | — | — | CN | disclosed |
| EP-0821690-B1 | Nucleotide analogues for the treatment of viral infections | USTAV ORGANICKE CHEMIE A BIOCHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) | 2012-06-13 | — | — | EP | disclosed |
| US-7709503-B2 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2006-10-05 | — | — | US | disclosed |
| US-5977061-A | VIRICIDE AGAINST DNA VIRUSES | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) | 1999-11-02 | — | — | US | disclosed |
| EP-0821690-A1 | NOVEL COMPOUNDS AND METHODS FOR THERAPY | Ustav Organicke Chemie A Biochemie Akademie Ved Ceske Republiky (CZ) | 1998-02-04 | — | — | EP | disclosed |
| US-5574149-A | Method of treating HIV infections with 2',3'-dideoxy-3'-fluoro-5-chlorouridine | GLAXO WELLCOME INC. (US) | 1996-11-12 | — | — | US | disclosed |
| WO-1996033200-A1 | NOVEL COMPOUNDS AND METHODS FOR THERAPY | ÚSTAV ORGANICKÉ CHEMIE A BIOCHEMIE AKADEMIE VED C^¿ESKÉ REPUBLIKY (CZ) | 1996-10-24 | — | — | WO | disclosed |
| EP-0670328-A1 | Therapeutic nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-09-06 | — | — | EP | disclosed |
| EP-0669341-A1 | Therapeutic Nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-08-30 | — | — | EP | disclosed |
| WO-1992003122-A1 | PREPARATION FOR APPLICATION OF ACTIVE SUBSTANCES IN THE FORM OF MINIMUM-SIZED DROPLETS | CEVC GREGOR (DE) | 1992-03-05 | — | — | WO | disclosed |
| EP-0317128-A2 | Anti-HIV Pyrimidine Nucleosides | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-05-24 | — | — | EP | disclosed |
| US-3996361-A | ANTIEDEMATOUS, REDUCING CAPILLARY PERMEABILITY | BOEHRINGER MANNHEIM G.M.B.H. (DT) | 1976-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | PEF1, PEPD, PELP1 | HTT 4108/4885AKT2 3163/4885LMNA 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.