Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA6 | P23280 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL5438151 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL11229397 | 0.93 | MAPT (0.50) | MAPTTDP1ALDH1A1LMNABLM | |
| Ethylenediamine SCHEMBL8414481 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL4840713 | 0.93 | NFKB1 (0.44) | MAPTTDP1ALDH1A1LMNABLM | |
| Ethylenediamine SCHEMBL11440118 | 0.93 | MAPT (0.50) | MAPTTDP1ALDH1A1LMNABLM | |
| Ethylenediamine SCHEMBL1331588 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL371485 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL5085636 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL5147148 | 0.93 | NFKB1 (0.44) | MAPTTDP1ALDH1A1LMNABLM | |
| Ethylenediamine SCHEMBL607065 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718803-B2 | Self-dispersible bipyridine-based metal complex and ink composition comprising the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2010-05-18 | — | — | US | disclosed |
| US-7396399-B2 | Bipyridine-based metal complex and ink composition comprising the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-07-08 | — | — | US | disclosed |
| US-20070269991-A1 | SEMICONDUCTOR NANOCRYSTAL-METAL COMPLEX AND METHOD OF PREPARING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2007-11-22 | — | — | US | disclosed |
| US-20050033040-A1 | Self-dispersible bipyridine-based metal complex and ink composition comprising the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2005-02-10 | — | — | US | disclosed |
| US-20050033053-A1 | Bipyridine-based metal complex and ink composition comprising the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2005-02-10 | — | — | US | disclosed |
| US-20040102654-A1 | Process facilitating the regeneration of a catalyst based on a zeolite used in an acylation reaction, catalyst and use | SPAGNOL MICHEL (FR) | 2004-05-27 | — | — | US | disclosed |
| US-20020120169-A1 | Process facilitating the regeneration of a catalyst based on a zeolite used in an acylation reaction, catalyst and use | SPAGNOL MICHEL (FR) | 2002-08-29 | — | — | US | disclosed |
| EP-0716931-B1 | Ink and sheet for ink jet recording and ink recording method | KONISHIROKU PHOTO IND (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5706042-A | CHELATION OF AZO OR INDOANILINE DYES WITH METAL, COLORFAST | KONICA CORPORATION (JP) | 1998-01-06 | — | — | US | disclosed |
| EP-0716931-A1 | Ink and sheet for ink jet recording and ink recording method | KONICA CORPORATION (JP) | 1996-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033040-A1 | Self-dispersible bipyridine-based metal complex and ink composition comprising the same | PDCD2L, BICRA, BRD1 | MAPT 1373/4885TDP1 3932/4885ALDH1A1 1418/4885 |
| US-20050033053-A1 | Bipyridine-based metal complex and ink composition comprising the same | TP53, BCCIP, CIP2A | MAPT 572/4885TDP1 2787/4885ALDH1A1 1475/4885 |
| US-20020120169-A1 | Process facilitating the regeneration of a catalyst based on a zeolite used in an acylation reaction, catalyst and use | AFF4, APEH, TECR | MAPT 4506/4885TDP1 4544/4885ALDH1A1 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.