SCHEMBL328744

SCHEMBL328744

[c]1c(Oc2ccccc2)ccc2c1ccc1ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.42
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 3/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP2A6 P11509 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LTA4H P09960 1/20 0.35
HIF1A Q16665 1/20 0.35
CYP1B1 Q16678 1/20 0.35
HTT P42858 2/20 0.34
PGR P06401 1/20 0.33
LMNA P02545 1/20 0.33
KDM1A O60341 1/20 0.33
KCNA3 P22001 1/20 0.33
PAX8 Q06710 1/20 0.32
ABCG2 Q9UNQ0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL328780 0.80 LTA4H (0.42) MAPTKDM4EGLAKMT2AALDH1A1
SCHEMBL8691514 0.79 HPRT1 (0.45) HPRT1MAPTKDM4EALDH1A1TSHR
SCHEMBL16909687 0.78 HPRT1 (0.48) HPRT1MAPTKDM4EALDH1A1TSHR
SCHEMBL328940 0.77 LTA4H (0.39) MAPTKDM4EGLAKMT2AALDH1A1
SCHEMBL10469538 0.75 HPRT1 (0.41) HPRT1MAPTKMT2AALDH1A1TSHR
SCHEMBL815764 0.70 HPRT1 (0.46) HPRT1MAPTKDM4EALDH1A1TSHR
SCHEMBL6436724 0.69 HPRT1 (0.50) HPRT1MAPTALDH1A1TSHRHSD17B10
SCHEMBL8571906 0.69 HPRT1 (0.50) HPRT1MAPTALDH1A1TSHRHSD17B10
SCHEMBL8693942 0.69 HPRT1 (0.50) HPRT1MAPTALDH1A1TSHRHSD17B10
SCHEMBL2139310 0.69 HPRT1 (0.50) HPRT1MAPTALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8900725-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. 2014-12-02 US claimed
US-8865322-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-21 US claimed
EP-2407501-B1 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO LTD (KR) 2013-09-11 EP claimed
EP-2407502-B1 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO LTD (KR) 2013-06-19 EP claimed
US-20120013246-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US claimed
US-20120013247-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US claimed
EP-2407501-A1 Dendrimer and organic light-emitting device using the same Samsung Mobile Display Co., Ltd. (KR) 2012-01-18 EP claimed
EP-2407502-A1 Dendrimer and organic light-emitting device using the same Samsung Mobile Display Co., Ltd. (KR) 2012-01-18 EP claimed
US-8900725-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. 2014-12-02 US disclosed
US-8865322-B2 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-21 US disclosed
EP-2407501-B1 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO LTD (KR) 2013-09-11 EP disclosed
EP-2407502-B1 Dendrimer and organic light-emitting device using the same SAMSUNG DISPLAY CO LTD (KR) 2013-06-19 EP disclosed
US-20120013246-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US disclosed
US-20120013247-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-01-19 US disclosed
EP-2407501-A1 Dendrimer and organic light-emitting device using the same Samsung Mobile Display Co., Ltd. (KR) 2012-01-18 EP disclosed
EP-2407502-A1 Dendrimer and organic light-emitting device using the same Samsung Mobile Display Co., Ltd. (KR) 2012-01-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120013247-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CLTB, CD40LG, DYNLL2 HPRT1 1715/4885MAPT 446/4885KDM4E 3262/4885
US-20120013246-A1 DENDRIMER AND ORGANIC LIGHT-EMITTING DEVICE USING THE SAME CLTB, CD40LG, DYNLL2 HPRT1 1715/4885MAPT 446/4885KDM4E 3262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.