SCHEMBL3287449

SCHEMBL3287449

CCC(C)([N+](=O)[O-])[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
TSHR P16473 4/20 0.42
TDP1 Q9NUW8 2/20 0.37
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9497771 0.78 ALDH1A1 (0.47) ALDH1A1TSHRTDP1LMNA
SCHEMBL1170397 0.75
SCHEMBL1700893 0.73 LMNA (0.48) ALDH1A1TSHRTDP1LMNA
SCHEMBL1998822 0.73 ALDH1A1 (0.50) ALDH1A1TSHRTDP1
SCHEMBL9452595 0.71 TSHR (0.44) ALDH1A1TSHRTDP1LMNA
SCHEMBL28700908 0.71
SCHEMBL5356080 0.71
SCHEMBL1170447 0.71 ALDH1A1 (0.41) ALDH1A1TSHRTDP1
SCHEMBL1170452 0.71 ALDH1A1 (0.41) ALDH1A1TSHRTDP1
SCHEMBL19210077 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103012194-B Nitrine ester compound and synthesis method thereof UNIV NANJING SCIENCE & TECH 2014-09-17 CN claimed
CN-103012194-A Nitrine ester compound and synthesis method thereof UNIV NANJING SCIENCE & TECH 2013-04-03 CN claimed
EP-1000011-A4 PREPARATION OF TETRAMETHYLETHYLENEDIAMINE HAMPSHIRE CHEMICAL CORP (US) 2001-09-19 EP claimed
EP-1000011-A1 PREPARATION OF TETRAMETHYLETHYLENEDIAMINE HAMPSHIRE CHEMICAL CORPORATION (US) 2000-05-17 EP claimed
WO-1999006350-A1 PREPARATION OF TETRAMETHYLETHYLENEDIAMINE HAMPSHIRE CHEMICAL CORP. (US) 1999-02-11 WO claimed
US-9227910-B2 Gem-dinitro ester energetic material using esterification and preparation method thereof AGENCY FOR DEFENCE DEVELOPMENT (KR) 2016-01-05 US disclosed
US-9227910-B2 Gem-dinitro ester energetic material using esterification and preparation method thereof AGENCY FOR DEFENCE DEVELOPMENT (KR) 2016-01-05 US disclosed
CN-104045566-A Fatty acid ester compounds of 2, 3-dihydroxymethyl-2, 3-dinitro-1, 4-butanediol and synthesis method thereof UNIV NANJING SCIENCE & TECH 2014-09-17 CN disclosed
CN-103012194-B Nitrine ester compound and synthesis method thereof UNIV NANJING SCIENCE & TECH 2014-09-17 CN disclosed
CN-103641723-A 2,3-Dihydroxymethyl-2,3-dinitro-1,4-butanediol tetraacetate and synthetic method thereof UNIV NANJING SCIENCE & TECH 2014-03-19 CN disclosed
EP-2646794-A1 METHOD FOR DETECTING IN SITU THE PRESENCE OF EXPLOSIVES IN A GASEOUS MEDIUM Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2013-10-09 EP disclosed
CN-102267913-B Synthetic method of 2,3-dimethyl-2,3-dinitrobutane NINGBO INST TECH ZHEJIANG UNIV 2013-06-12 CN disclosed
CN-103012194-A Nitrine ester compound and synthesis method thereof UNIV NANJING SCIENCE & TECH 2013-04-03 CN disclosed
WO-2012072582-A1 METHOD FOR DETECTING IN SITU THE PRESENCE OF EXPLOSIVES IN A GASEOUS MEDIUM Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2012-06-07 WO disclosed
US-7713401-B2 Methods for performing electrochemical nitration reactions BATTELLE ENERGY ALLIANCE, LLC (US) 2010-05-11 US disclosed
US-20090038953-A1 METHODS FOR PERFORMING ELECTROCHEMICAL NITRATION REACTIONS ENERGY, UNITED STATES DEPARTMENT OF 2009-02-12 US disclosed
WO-2009020798-A1 METHODS FOR PERFORMING ELECTROCHEMICAL NITRATION REACTIONS BATTELLE ENERGY ALLIANCE, LLC (US) 2009-02-12 WO disclosed
EP-1000011-A4 PREPARATION OF TETRAMETHYLETHYLENEDIAMINE HAMPSHIRE CHEMICAL CORP (US) 2001-09-19 EP disclosed
EP-1000011-A1 PREPARATION OF TETRAMETHYLETHYLENEDIAMINE HAMPSHIRE CHEMICAL CORPORATION (US) 2000-05-17 EP disclosed
WO-1999006350-A1 PREPARATION OF TETRAMETHYLETHYLENEDIAMINE HAMPSHIRE CHEMICAL CORP. (US) 1999-02-11 WO disclosed