SCHEMBL3287596

SCHEMBL3287596

COc1cc2c(c(OC)c1)OC1(/C=C\C=C/2)N(C)c2ccccc2C1(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.46
GAA P10253 4/20 0.46
LMNA P02545 4/20 0.46
RECQL P46063 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
NPSR1 Q6W5P4 3/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ALOX15 P16050 2/20 0.46
ALPG P10696 1/20 0.46
TP53 P04637 1/20 0.46
HSD17B10 Q99714 1/20 0.46
THRB P10828 5/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
PKM P14618 2/20 0.45
PLIN1 O60240 1/20 0.45
TSHR P16473 1/20 0.45
PLIN5 Q00G26 1/20 0.45
ABHD5 Q8WTS1 1/20 0.45
KDM4E B2RXH2 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3287603 1.00 MAPT (0.46) MAPTGAALMNARECQLTDP1
SCHEMBL3287910 0.86 MAPT (0.43) MAPTGAALMNARECQLTDP1
SCHEMBL3287913 0.86 MAPT (0.43) MAPTGAALMNARECQLTDP1
SCHEMBL13359696 0.86 MAPT (0.43) MAPTGAALMNARECQLTDP1
SCHEMBL3294116 0.83 MAPT (0.64) MAPTGAALMNARECQLTDP1
SCHEMBL3294107 0.83 MAPT (0.64) MAPTGAALMNARECQLTDP1
SCHEMBL8684929 0.81 MAPT (0.64) MAPTGAALMNARECQLTDP1
SCHEMBL8680395 0.81 MAPT (0.53) MAPTGAALMNARECQLTDP1
SCHEMBL8680969 0.81 MAPT (0.53) MAPTGAALMNARECQLTDP1
SCHEMBL13326515 0.78 MAPT (0.50) MAPTGAALMNARECQLTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718325-B2 Photochromic material, inkless reimageable printing paper, and methods XEROX CORPORATION (US) 2010-05-18 US disclosed
US-7718325-B2 Photochromic material, inkless reimageable printing paper, and methods XEROX CORPORATION (US) 2010-05-18 US disclosed
US-7718325-B2 Photochromic material, inkless reimageable printing paper, and methods XEROX CORPORATION (US) 2010-05-18 US disclosed
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS XEROX CORPORATION (US) 2008-12-18 US disclosed
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS XEROX CORPORATION (US) 2008-12-18 US disclosed
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS XEROX CORPORATION (US) 2008-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS ILK, RB1, SMCHD1 MAPT 246/4885GAA 3865/4885LMNA 1767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.