SCHEMBL3294107

SCHEMBL3294107

COc1ccc2c(c1)/C=C\C=C/C1(O2)N(C)c2ccccc2C1(C)C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.64
THRB P10828 5/20 0.64
GAA P10253 4/20 0.64
LMNA P02545 4/20 0.64
SMN1; SMN2 Q16637 4/20 0.64
RECQL P46063 3/20 0.64
TDP1 Q9NUW8 3/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
PKM P14618 2/20 0.64
PLIN1 O60240 1/20 0.64
TSHR P16473 1/20 0.64
PLIN5 Q00G26 1/20 0.64
ABHD5 Q8WTS1 1/20 0.64
NPSR1 Q6W5P4 4/20 0.61
ALOX15 P16050 2/20 0.61
ALPG P10696 1/20 0.61
TP53 P04637 1/20 0.61
HSD17B10 Q99714 1/20 0.61
KDM4E B2RXH2 6/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3294116 1.00 MAPT (0.64) MAPTTHRBGAALMNASMN1; SMN2
SCHEMBL8680078 0.92 MAPT (0.74) MAPTTHRBGAALMNASMN1; SMN2
SCHEMBL8680159 0.83 MAPT (0.61) MAPTTHRBGAALMNASMN1; SMN2
SCHEMBL3287603 0.83 MAPT (0.46) MAPTTHRBGAALMNASMN1; SMN2
SCHEMBL3287596 0.83 MAPT (0.46) MAPTTHRBGAALMNASMN1; SMN2
SCHEMBL3289455 0.82 MAPT (0.60) MAPTTHRBGAALMNASMN1; SMN2
SCHEMBL3289449 0.82 MAPT (0.60) MAPTTHRBGAALMNASMN1; SMN2
SCHEMBL8682721 0.79 MAPT (0.56) MAPTTHRBGAALMNASMN1; SMN2
SCHEMBL8681722 0.78 MAPT (0.56) MAPTTHRBGAALMNASMN1; SMN2
SCHEMBL8684751 0.77 MAPT (0.76) MAPTTHRBGAALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718325-B2 Photochromic material, inkless reimageable printing paper, and methods XEROX CORPORATION (US) 2010-05-18 US disclosed
US-7718325-B2 Photochromic material, inkless reimageable printing paper, and methods XEROX CORPORATION (US) 2010-05-18 US disclosed
US-7718325-B2 Photochromic material, inkless reimageable printing paper, and methods XEROX CORPORATION (US) 2010-05-18 US disclosed
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS XEROX CORPORATION (US) 2008-12-18 US disclosed
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS XEROX CORPORATION (US) 2008-12-18 US disclosed
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS XEROX CORPORATION (US) 2008-12-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311495-A1 PHOTOCHROMIC MATERIAL, INKLESS REIMAGEABLE PRINTING PAPER, AND METHODS ILK, RB1, SMCHD1 MAPT 246/4885THRB 3663/4885GAA 3865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.