Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | POLA1 | P09884 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862242 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL11860832 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL1365915 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL1366448 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL1363303 | 1.00 | TSHR (0.64) | TSHRLMNAALDH1A1KMT2ARECQL | |
| SCHEMBL1363541 | 0.98 | — | — | |
| SCHEMBL83390 | 0.90 | — | — | |
| SCHEMBL11432928 | 0.88 | ALDH1A1 (0.59) | TSHRLMNAALDH1A1RECQLFAAH | |
| SCHEMBL11432924 | 0.88 | ALDH1A1 (0.59) | TSHRLMNAALDH1A1RECQLFAAH | |
| SCHEMBL25824485 | 0.88 | TSHR (0.50) | TSHRLMNAALDH1A1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104497009-B | A kind of simple and convenient process for preparing of Bio | 新发药业有限公司 | 2016-08-24 | — | — | CN | claimed |
| CN-104497009-A | Simple method for preparing D-biotin | XINFA PHARMACEUTICAL CO LTD | 2015-04-08 | — | — | CN | claimed |
| CN-102659701-A | Synthesis of azacyclo-containing aminohexanoic acid | JIANDONG XIU | 2012-09-12 | — | — | CN | claimed |
| CN-102633671-A | Method for preparing n-undecarbamide diacid | JIANDONG XIU | 2012-08-15 | — | — | CN | claimed |
| US-11124617-B2 | Materials coated with calixarenes | UNIVERSITE LIBRE DE BRUXELLES (ULB) (BE) | 2021-09-21 | — | — | US | disclosed |
| EP-2836539-B1 | MATERIALS COATED WITH CALIXARENES | UNIV LIBRE DE BRUXELLES ULB (BE) | 2019-09-18 | — | — | EP | disclosed |
| US-20190233358-A1 | MATERIALS COATED WITH CALIXARENES | UNIVERSITE LIBRE DE BRUXELLES (ULB) (BE) | 2019-08-01 | — | — | US | disclosed |
| US-10329232-B2 | Materials coated with calixarenes | UNIVERSITE LIBRE DE BRUXELLES (ULB) (BE) | 2019-06-25 | — | — | US | disclosed |
| CN-104487496-B | The material coated through calixarenes | 布鲁塞尔私立大学 | 2018-09-18 | — | — | CN | disclosed |
| CN-104497009-B | A kind of simple and convenient process for preparing of Bio | 新发药业有限公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-104497009-A | Simple method for preparing D-biotin | XINFA PHARMACEUTICAL CO LTD | 2015-04-08 | — | — | CN | disclosed |
| CN-104487496-A | Materials coated with calixarenes | UNIV LIBRE DE BRUXELLES ULB | 2015-04-01 | — | — | CN | disclosed |
| EP-0156611-B1 | INTERMEDIATES FOR THE PREPARATION OF PROSTAGLANDIN ANALOGUES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |
| EP-0260134-A2 | Fatty peroxyacids or salts thereof having amide moieties in the fatty chain and low levels of exotherm control agents and detergent compositions containing the same | THE PROCTER & GAMBLE COMPANY (US) | 1988-03-16 | — | — | EP | disclosed |
| US-4686063-A | STABILIZERS FOR DETERGENT BLEACHES | THE PROCTER & GAMBLE COMPANY (US) | 1987-08-11 | — | — | US | disclosed |
| US-4634551-A | TEXTILE BLEACHING | PROCTER & GAMBLE COMPANY (US) | 1987-01-06 | — | — | US | disclosed |
| US-4622410-A | CHEMICAL INTERMEDIATES FOR 6-KETO-PROSTAGLANDINS | ONO PHARMACEUTICAL CO. LTD. (JP) | 1986-11-11 | — | — | US | disclosed |
| EP-0170386-A2 | Bleaching compounds and compositions comprising fatty peroxy acids, salts thereof, and precursors therefor | THE PROCTER & GAMBLE COMPANY (US) | 1986-02-05 | — | — | EP | disclosed |
| EP-0156611-A2 | Intermediates for the preparation of prostaglandin analogues | ONO PHARMACEUTICAL CO., LTD. (JP) | 1985-10-02 | — | — | EP | disclosed |
| US-4234744-A | Process for the production of aminoacid hydrochlorides/or diaminoacid dihydrochlorides | DEUTSCHE GOLD- UND SILBER SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124617-B2 | Materials coated with calixarenes | CALD1, CALU, CALR | TSHR 3988/4885LMNA 2985/4885ALDH1A1 1356/4885 |
| US-10329232-B2 | Materials coated with calixarenes | CALU, CALD1, CALR | TSHR 3774/4885LMNA 2709/4885ALDH1A1 1645/4885 |
| US-20190233358-A1 | MATERIALS COATED WITH CALIXARENES | CALD1, CALU, CALR | TSHR 3988/4885LMNA 2985/4885ALDH1A1 1356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.