SCHEMBL328792

SCHEMBL328792

Oc1ccc(-n2ccnc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 1.00
MKNK1 Q9BUB5 1/20 1.00
MKNK2 Q9HBH9 1/20 1.00
LMNA P02545 1/20 0.64
MAPT P10636 1/20 0.64
NOTUM Q6P988 1/20 0.64
CYP3A4 P08684 5/20 0.63
MEN1 O00255 1/20 0.60
ALOX15 P16050 1/20 0.60
TSHR P16473 1/20 0.60
KMT2A Q03164 1/20 0.60
BAZ2B Q9UIF8 1/20 0.59
ADH5 P11766 1/20 0.56
TNIK Q9UKE5 1/20 0.55
HTT P42858 1/20 0.54
CYP51A1 Q16850 1/20 0.53
HTR2A P28223 1/20 0.53
HTR2C P28335 1/20 0.53
HTR2B P41595 1/20 0.53
CYP2A6 P11509 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28181855 0.98 ENPP2 (0.96) ENPP2MKNK1MKNK2LMNAMAPT
SCHEMBL28428741 0.98 ENPP2 (0.96) ENPP2MKNK1MKNK2LMNAMAPT
SCHEMBL28239036 0.94 ENPP2 (0.89) ENPP2MKNK1MKNK2LMNAMAPT
SCHEMBL11072227 0.89 ENPP2 (0.79) ENPP2MKNK1MKNK2LMNAMAPT
SCHEMBL2532397 0.89 LMNA (0.78) ENPP2MKNK1MKNK2LMNAMAPT
Hydrochloric Acid SCHEMBL28701756 0.86 LMNA (0.75) ENPP2MKNK1MKNK2LMNAMAPT
SCHEMBL28737980 0.83 ENPP2 (0.70) ENPP2MKNK1MKNK2LMNAMAPT
SCHEMBL2533488 0.82 TSHR (0.84) ENPP2MKNK1MKNK2LMNAMAPT
SCHEMBL28262661 0.81 ENPP2 (0.68) ENPP2MKNK1MKNK2LMNAMAPT
Benzylimidazole SCHEMBL21708930 0.80 CYP11B1 (0.67) ENPP2MKNK1MKNK2MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 844 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567437-A Bis-imidazole ionic liquid and application thereof as catalyst in preparation of ethylene carbonate 山东海科创新研究院有限公司 2024-02-20 CN claimed
CN-114088937-B Kit for detecting echinococcosis antibody based on chemiluminescence immunoassay technology, and preparation method and use method thereof 新疆医科大学 2023-08-29 CN claimed
CN-113512003-B Preparation method of 4- (imidazole-1-yl) phenol 上海瀚诺威生物科技有限公司 2022-08-30 CN claimed
CN-114805597-A Recombinant TetR protein, preparation method and kit thereof, and detection method of tetracycline antibiotic residue in milk 河北农业大学 2022-07-29 CN claimed
CN-113769780-B Magnetic microsphere-loaded bi-acidic ionic liquid catalyst and preparation and application thereof 浙江吉泰新材料股份有限公司 2022-05-03 CN claimed
CN-114088937-A Kit for detecting echinococcosis antibody based on chemiluminescence immunoassay technology, and preparation method and use method thereof 新疆医科大学 2022-02-25 CN claimed
CN-113769780-A Magnetic microsphere-loaded bi-acidic ionic liquid catalyst and preparation and application thereof 浙江吉泰新材料股份有限公司 2021-12-10 CN claimed
CN-109187509-B Chemiluminescent kit for specific detection of chloramphenicol, detection method and application 河北农业大学 2021-11-12 CN claimed
CN-113512003-A Preparation method of 4- (imidazole-1-yl) phenol 上海瀚诺威生物科技有限公司 2021-10-19 CN claimed
CN-109001188-B Specific molecularly imprinted polymer of adamantanamine and rimantadine, chemiluminescence kit, detection method and application 河北农业大学 2021-09-14 CN claimed
EP-0496793-B1 ENHANCED CHEMILUMINESCENT ASSAY BRITISH TECH GROUP (GB) 1995-12-20 EP claimed
US-5356921-A Exhibit 5-lipoxygenase and thromboxane synthase inhibiting activities; administering for disorders attributable to the action of leukotrienes and thromboxane A2 GRUENENTHAL GMBH (DE) 1994-10-18 US claimed
WO-1994023060-A2 ENHANCEMENT OF CHEMILUMINESCENT REACTIONS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-10-13 WO claimed
US-5306621-A Enhanced chemiluminescent assay BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-04-26 US claimed
EP-0251760-B1 Rubber composition BRIDGESTONE CORP (JP) 1994-01-26 EP claimed
EP-0557787-A1 Imidazolylphenol derivatives, medicaments containing them and a process for the preparation of these compounds and medicaments Grünenthal GmbH (DE) 1993-09-01 EP claimed
US-5140055-A Improved high speed grip performance BRIDGESTONE CORPORATION (JP) 1992-08-18 US claimed
EP-0296752-B1 ENHANCED CHEMILUMINESCENT REACTION AND DIAGNOSTIC ASSAY BTG INTERNATIONAL LIMITED (GB) 1992-03-25 EP claimed
EP-0296752-A1 Enhanced chemiluminescent reaction and diagnostic assay BTG INTERNATIONAL LIMITED (GB) 1988-12-28 EP claimed
US-4500540-A DIETETICS HOFFMANN-LA ROCHE INC. (US) 1985-02-19 US claimed