SCHEMBL3287952

SCHEMBL3287952

CCC(C)c1cc(C(C)(C)C)cc(-c2ccccc2-c2c[nH]nn2)c1O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
RORC P51449 1/20 0.39
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
NR2F2 P24468 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10434421 0.81 RAB9A (0.35) TSHRCYP1A2CYP2C9CYP2C19MEN1
SCHEMBL3220777 0.80 HSP90AA1 (0.44) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL30481081 0.77 TSHR (0.39) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL4637460 0.77 TSHR (0.39) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL27303604 0.76 TSHR (0.51) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL669252 0.74 MEN1 (0.44) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL2051851 0.74 MAPK1 (0.37) MEN1NPC1RAB9AKMT2A
Benzotriazole SCHEMBL28649888 0.72 CYP1A2 (0.41) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL199728 0.72 RORC (0.58) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL7059072 0.71 TNF (0.47) TSHRCYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9562148-B2 Basic stabilisation systems for emulsion polymerised rubber BASF SE (DE) 2017-02-07 US disclosed
US-20160046789-A1 BASIC STABILISATION SYSTEMS FOR EMULSION POLYMERISED RUBBER BASF SE (DE) 2016-02-18 US disclosed
US-8609807-B2 Method of producing low-dust granules from polymer additives BASF SE (DE) 2013-12-17 US disclosed
US-7713444-B2 Mixtures of sterically hindered amines for the stabilisation of polymers 3V SIGMA S.P.A. (IT) 2010-05-11 US disclosed
US-20090270535-A1 MIXTURES OF STERICALLY HINDERED AMINES FOR THE STABILISATION OF POLYMERS 3V SIGMA S.P.A. (IT) 2009-10-29 US disclosed
EP-2112198-A1 Mixtures of sterically hindered amines for the stabilisation of polymers 3V SIGMA S.p.A (IT) 2009-10-28 EP disclosed
US-20090194617-A1 Method of producing low-dust granules from polymer additives CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2009-08-06 US disclosed
US-20090169745-A1 Nanoparticle based inks and methods of making the same KIMBERLY-CLARK WORLDWIDE, INC. 2009-07-02 US disclosed
EP-1392779-B1 FLUORINATED-PHOTOINITIATORS IN DUAL CURE RESINS CIBA HOLDING INC (CH) 2009-04-22 EP disclosed
US-20080152810-A1 NANOPARTICLE BASED INKS AND METHODS OF MAKING THE SAME KIMBERLY-CLARK WORDWIDE, INC. 2008-06-26 US disclosed
US-6376568-B1 MODIFIED POLYSILOXANE CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-23 US disclosed
US-6228157-B1 CONTAINING A COLORANT, AT LEAST ONE WATER-SOLUBLE COMPOUND, AND A COLORANT STABILIZER WHEREIN THE COLORANT STABILIZER COMPRISES A PORPHINE INTELLECTUAL VENTURES ASSETS 158 LLC 2001-05-08 US disclosed
WO-2000059620-A1 IMPROVED SURFACTANT AND INK JET INK COMPOSITIONS CONTAINING THE SAME KIMBERLY-CLARK WORLDWIDE, INC. (US) 2000-10-12 WO disclosed
EP-0909298-A1 STABILISATION OF PAINTS WITH SPIROINDANE DERIVATIVES Ciba SC Holding AG (CH) 1999-04-21 EP disclosed
US-5855655-A INKS OF THE INK SET POSSESS SUBSTANTIALLY SIMILAR LIGHT FASTNESS PROPERTIES, ONE INK IS MAGENTA KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-01-05 US disclosed
WO-1998001507-A1 STABILISATION OF PAINTS WITH SPIROINDANE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1998-01-15 WO disclosed
EP-0799254-A1 PYRROLIDINONE-CONTAINING COMPATIBILISERS Ciba SC Holding AG (CH) 1997-10-08 EP disclosed
WO-1996019507-A1 PYRROLIDINONE-CONTAINING COMPATIBILISERS CIBA SPECIALITY CHEMICALS HOLDING INC. (CH) 1996-06-27 WO disclosed
US-4906555-A Silver halide color photographic material comprising specified couplers and anti-fading agents FUJI PHOTO FILM CO., LTD. (JP) 1990-03-06 US disclosed
US-4543322-A STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1985-09-24 US disclosed