Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817419 | 0.79 | HPGD (0.56) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL1357094 | 0.75 | HPGD (0.52) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL21685 | 0.75 | HPGD (0.52) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| Salicylamide SCHEMBL28133155 | 0.75 | KDM4E (0.95) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| Salicylamide SCHEMBL27724027 | 0.73 | KDM4E (0.91) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL9641182 | 0.73 | KDM4E (0.54) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| Salicylic Acid SCHEMBL1193531 | 0.73 | ALDH1A1 (0.86) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| Salicylic Acid SCHEMBL1810677 | 0.73 | ALDH1A1 (0.86) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL324637 | 0.73 | HPGD (0.62) | HPGDKDM4EALDH1A1HSD17B10MAPT | |
| Salicylamide SCHEMBL21646 | 0.72 | KDM4E (1.00) | HPGDKDM4EALDH1A1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2407164-A1 | Copper II complexes of phenanthroline and their use in cancer treatment | Dublin Institute of Technology Intellectual Property Ltd (IE) | 2012-01-18 | — | — | EP | disclosed |