SCHEMBL3287976

SCHEMBL3287976

CC(c1ccc(O)c(C(C)(C)C)c1)c1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.57
ALOX15 P16050 4/20 0.57
HTT P42858 2/20 0.57
HSD17B10 Q99714 2/20 0.57
LMNA P02545 2/20 0.57
NR1I2 O75469 1/20 0.57
CYP2C9 P11712 1/20 0.57
MIF P14174 1/20 0.57
TYR P14679 1/20 0.57
NFE2L2 Q16236 1/20 0.57
CYP1A2 P05177 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MAPT P10636 1/20 0.50
ATP2A2 P16615 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ATP2A3 Q93084 1/20 0.50
TDP1 Q9NUW8 2/20 0.45
TSHR P16473 1/20 0.45
ESR1 P03372 1/20 0.43
PDCD1 Q15116 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3285515 0.93 ALDH1A1 (0.60) ALDH1A1ALOX15HTTHSD17B10LMNA
SCHEMBL10411970 0.91 ALDH1A1 (0.48) ALDH1A1ALOX15HTTHSD17B10LMNA
SCHEMBL5164240 0.88 ALDH1A1 (0.57) ALDH1A1ALOX15HTTHSD17B10LMNA
SCHEMBL31388034 0.88 ALDH1A1 (0.57) ALDH1A1ALOX15HTTHSD17B10LMNA
SCHEMBL11588725 0.86 ALDH1A1 (0.55) ALDH1A1ALOX15HTTHSD17B10LMNA
SCHEMBL1597576 0.85 ALDH1A1 (0.59) ALDH1A1ALOX15HTTHSD17B10LMNA
SCHEMBL30343447 0.85 ALDH1A1 (0.59) ALDH1A1ALOX15HTTHSD17B10LMNA
SCHEMBL11590553 0.84 ALDH1A1 (0.53) ALDH1A1ALOX15HTTHSD17B10LMNA
SCHEMBL1596482 0.83 ALDH1A1 (0.57) ALDH1A1ALOX15HTTHSD17B10LMNA
SCHEMBL27999663 0.82 ALDH1A1 (0.52) ALDH1A1ALOX15HTTHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7718337-B2 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2010-05-18 US disclosed
US-20090081570-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR MITSUBISHI CHEMICAL CORPORATION (JP) 2009-03-26 US disclosed
US-7473507-B2 Electrophotographic photoreceptor with polyester resin in photosensitive layer MITSUBISHI CHEMICAL CORPORATION (JP) 2009-01-06 US disclosed
US-20060073400-A1 Electrophotographic photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2006-04-06 US disclosed
US-6603035-B1 A method for producing a high purity cyanate comprising reacting a phenol compound represented by the following formula SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-05 US disclosed
US-4522735-A Polyphosphoramidite oligomers and stabilizer compositions thereof THE B. F. GOODRICH COMPANY (US) 1985-06-11 US disclosed
EP-0019103-A1 Epoxide resins containing phenol groups, their use and plastics compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-26 EP disclosed