NDUFC1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Auraptene (SCHEMBL2535029)	1.00	5/20
Auraptene (SCHEMBL2535034)	1.00	5/20
SCHEMBL8491443	0.56	4/20
SCHEMBL8489900	0.52	4/20
SCHEMBL8489907	0.52	4/20
SCHEMBL8489902	0.51	4/20
SCHEMBL8489908	0.51	4/20
SCHEMBL8491154	0.51	4/20
SCHEMBL8491160	0.51	4/20
SCHEMBL8491619	0.50	4/20
SCHEMBL8491624	0.50	4/20
SCHEMBL8491634	0.50	4/20
7-Prenyloxycoumarin (SCHEMBL4898255)	0.79	3/20
SCHEMBL712741	0.57	3/20
Geiparvarin (SCHEMBL2532495)	0.56	3/20
SCHEMBL6267768	0.55	3/20
SCHEMBL1095981	0.55	3/20
SCHEMBL4293165	0.55	3/20
SCHEMBL8490928	0.53	3/20
SCHEMBL8490937	0.53	3/20

Clinical trials — most relevant to NDUFC1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Phase III Trial of Coenzyme Q10 in Mitochondrial Disease	PHASE3	COMPLETED
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder	PHASE2	WITHDRAWN
A Study of Bezafibrate in Mitochondrial Myopathy	PHASE2	COMPLETED
A Study to Evaluate Vitamin B3 Derivative to Treat Mitochondrial Myopathy	PHASE2	ACTIVE_NOT_RECRUITING
Trial of Nicotinamide Riboside and Co-enzyme Q10 in Chronic Kidney Disease	PHASE2	COMPLETED
Does Clinical Treatment of Mitochondrial Dysfunction Impact Autism Spectrum Disorder (ASD)?	PHASE1	UNKNOWN
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)	nan	RECRUITING
Genomic Profiling of Mitochondrial Disease - Imaging Analysis for Precise Mitochondrial Medicine	nan	COMPLETED
The Natural History of Mitochondrial Diseases	nan	RECRUITING
Tissue Sample Study for Mitochondrial Disorders	nan	ENROLLING_BY_INVITATION
Survey on Supplement Use in Mitochondrial Disease	nan	COMPLETED
Diagnostic Odyssey Survey 2	nan	COMPLETED
GDF-15 as a Biomarker for Mitochondrial Disease	nan	COMPLETED
Natural History in Primary Mitochondrial Myopathies	nan	RECRUITING
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases	nan	RECRUITING
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes	nan	NOT_YET_RECRUITING
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip	nan	COMPLETED
Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection	nan	COMPLETED
Nicotinamide Riboside and Mitochondrial Biogenesis	nan	COMPLETED
Identification of Large-Scale Mutations of POLG Gene by QMPSF in Patients With Mitochondrial DNA Instability.	nan	UNKNOWN
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants	nan	RECRUITING
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction	nan	COMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Calf Muscle Strength in Mitochondrial Diseases	nan	COMPLETED
The Genetics of Diabetes in Southern California Chinese Americans	nan	WITHDRAWN
Mitochondrial Dysfunctions Driving Insulin Resistance	nan	COMPLETED
Ccf mtDNA as a Neurodegenerative Biomarker	nan	UNKNOWN
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS	nan	RECRUITING
Plasma Cytochrome c as Biomarker of Traumatic Injury and Predictor of Outcome	nan	COMPLETED
Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a NDUFC1 binder may also engage these)

Protein	Name	Similarity
Q0MQF6	—	1.000	Q0MQF6 →
P0CB69	—	1.000	P0CB69 →
P0CB70	—	0.999	P0CB70 →
Q0MQF5	—	0.999	Q0MQF5 →
Q02376	—	0.994	Q02376 →
Q9CQY9	—	0.992	Q9CQY9 →
Q863G0	—	0.987	Q863G0 →
P60182	—	0.986	P60182 →
Q863G5	—	0.986	Q863G5 →
P60183	—	0.985	P60183 →
Q8SQ79	—	0.984	Q8SQ79 →
Q8SPI5	—	0.984	Q8SPI5 →
P10175	—	0.984	P10175 →
Q862Z9	—	0.984	Q862Z9 →
P60181	—	0.984	P60181 →
Q0MQC7	—	0.983	Q0MQC7 →
Q863G6	—	0.983	Q863G6 →
P80433	—	0.983	P80433 →
Q863G1	—	0.983	Q863G1 →
Q863G2	—	0.982	Q863G2 →
Q863G3	—	0.982	Q863G3 →
Q7JX57	—	0.981	Q7JX57 →
Q0MQJ3	—	0.981	Q0MQJ3 →
Q863F8	—	0.981	Q863F8 →
Q8TF08	—	0.980	Q8TF08 →
Q863F9	—	0.980	Q863F9 →
Q863G7	—	0.980	Q863G7 →
Q4R648	—	0.980	Q4R648 →
Q0MQC8	—	0.980	Q0MQC8 →
Q863G4	—	0.980	Q863G4 →