Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 11/20 | 0.57 |
| ▸ | ERCC4 | Q92889 | 11/20 | 0.57 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108628 | 0.77 | ERCC1 (0.79) | ERCC1ERCC4TRPV1 | |
| SCHEMBL28368385 | 0.75 | ERCC1 (0.79) | ERCC1ERCC4LCKTRPV1 | |
| SCHEMBL109055 | 0.75 | ADRB3 (0.65) | ADRB2ADRB1ADRB3 | |
| SCHEMBL14163016 | 0.73 | ERCC1 (1.00) | ERCC1ERCC4LCKTRPV1 | |
| SCHEMBL8108684 | 0.73 | ALOX15 (0.59) | ERCC1ERCC4ADRB2LCK | |
| SCHEMBL7947252 | 0.73 | ERCC1 (0.65) | ERCC1ERCC4LCKTRPV1 | |
| SCHEMBL6489950 | 0.72 | KMT2A (0.54) | ERCC1ERCC4ADRB2ADRB1ADRB3 | |
| SCHEMBL6364316 | 0.70 | ERCC1 (0.72) | ERCC1ERCC4KDM6B | |
| SCHEMBL175299 | 0.70 | ERCC1 (0.66) | ERCC1ERCC4LCKTRPV1 | |
| SCHEMBL107288 | 0.70 | ERCC1 (0.66) | ERCC1ERCC4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714170-B2 | Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs; Alzheimer's disease; diabetes; A beta amyloidosis | PROTEOTECH, INC. (US) | 2010-05-11 | — | — | US | claimed |