Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3280744 | 0.92 | ABCC2 (0.40) | — | |
| SCHEMBL3285118 | 0.92 | TOP2A (0.42) | TOP2ANAPEPLD | |
| SCHEMBL3287716 | 0.91 | TOP2A (0.40) | TOP2A | |
| SCHEMBL3281921 | 0.91 | ABCC2 (0.39) | — | |
| SCHEMBL3282208 | 0.90 | TOP2A (0.47) | TOP2ANAPEPLD | |
| SCHEMBL3281720 | 0.90 | ABCC2 (0.42) | — | |
| SCHEMBL3285052 | 0.86 | ABCC2 (0.41) | — | |
| SCHEMBL3281707 | 0.85 | ALDH1A1 (0.45) | — | |
| SCHEMBL3281645 | 0.85 | ABCC2 (0.40) | — | |
| SCHEMBL3280633 | 0.85 | ABCC2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709503-B2 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | PEF1, PEPD, PELP1 | TOP2A 1582/4885NAPEPLD 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.