SCHEMBL32889359

SCHEMBL32889359

COc1ccc(Cl)c2c1OCCO2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
KDM4E B2RXH2 3/20 0.54
ALDH1A1 P00352 3/20 0.54
HSD17B10 Q99714 1/20 0.54
MAPT P10636 2/20 0.42
MAOB P27338 1/20 0.40
HTR2A P28223 4/20 0.39
HTR2C P28335 4/20 0.39
HTR2B P41595 4/20 0.39
EGFR P00533 2/20 0.37
HTT P42858 2/20 0.37
GAA P10253 1/20 0.37
NPC1 O15118 1/20 0.37
KMT2A Q03164 1/20 0.36
S1PR4 O95977 1/20 0.35
HSP90AA1 P07900 1/20 0.35
G6PD P11413 1/20 0.35
S1PR1 P21453 1/20 0.35
MAPK1 P28482 1/20 0.35
OPRK1 P41145 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15988845 0.87 KDM4E (0.66) LMNAKDM4EALDH1A1HSD17B10MAPT
SCHEMBL10436242 0.80 HTR2A (0.39) LMNAHTR2AHTR2CHTR2BHTT
SCHEMBL6605094 0.78 KDM4E (0.56) LMNAKDM4EALDH1A1HSD17B10MAPT
SCHEMBL15988872 0.76 LMNA (0.59) LMNAKDM4EALDH1A1HSD17B10MAPT
SCHEMBL31104487 0.74 LMNA (0.68) LMNAKDM4EALDH1A1HSD17B10MAPT
SCHEMBL25366488 0.73 ALDH1A1 (0.50) LMNAKDM4EALDH1A1HSD17B10MAPT
SCHEMBL29361367 0.73 ALDH1A1 (0.50) LMNAKDM4EALDH1A1HSD17B10MAPT
SCHEMBL6606202 0.73 ALDH1A1 (0.56) LMNAKDM4EALDH1A1HSD17B10MAPT
SCHEMBL15988851 0.73 ALDH1A1 (0.56) LMNAKDM4EALDH1A1HSD17B10MAPT
SCHEMBL11271758 0.73 KDM4E (0.73) LMNAKDM4EALDH1A1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121758413-A Preparation method of 1- (5-methoxy-2, 3-dihydro-1, 4-benzodioxane-8-yl) ethanone 长沙贝塔医药科技有限公司 2026-03-31 CN disclosed