Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12475636 | 1.00 | KEAP1 (0.50) | KEAP1NFE2L2GAAHPGDCYP1A2 | |
| SCHEMBL370588 | 0.83 | KEAP1 (0.50) | KEAP1NFE2L2GAAHPGDCYP1A2 | |
| SCHEMBL1406090 | 0.83 | KEAP1 (0.50) | KEAP1NFE2L2GAAHPGDCYP1A2 | |
| SCHEMBL12476349 | 0.80 | DAO (0.56) | KEAP1NFE2L2GAAHPGDCYP1A2 | |
| SCHEMBL3524315 | 0.80 | KEAP1 (0.47) | KEAP1NFE2L2GAAHPGDCYP1A2 | |
| SCHEMBL296024 | 0.80 | KEAP1 (0.47) | KEAP1NFE2L2GAAHPGDCYP1A2 | |
| SCHEMBL2535316 | 0.80 | KEAP1 (0.51) | KEAP1NFE2L2GAAHPGDCYP1A2 | |
| SCHEMBL4424885 | 0.79 | NQO2 (0.57) | KEAP1NFE2L2GAAHPGDCYP1A2 | |
| SCHEMBL26262428 | 0.79 | KDM4E (0.39) | KEAP1NFE2L2GAAHPGDCYP1A2 | |
| SCHEMBL24038450 | 0.77 | KEAP1 (0.45) | KEAP1NFE2L2GAAHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121758344-A | Preparation method of 4-fluoro-5-hydroxy-2-methylindole | 常州佳德医药科技有限公司 | 2026-03-31 | — | — | CN | disclosed |