SCHEMBL3289174

SCHEMBL3289174

Cc1ccccc1-c1ccc(OP(=O)(O)O)c(C(C)(C)C)c1C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 8/20 0.39
INPP5A Q14642 4/20 0.39
AKT1 P31749 1/20 0.39
INPP5B P32019 2/20 0.37
SRC P12931 2/20 0.36
KDM4E B2RXH2 1/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
PDE3A Q14432 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.30
SLC6A9 P48067 1/20 0.30
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3287701 0.82 SRC (0.41) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL27826911 0.80 INPPL1 (0.47) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL3289172 0.78 INPPL1 (0.40) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL1043483 0.78 INPPL1 (0.50) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL28363917 0.78 INPPL1 (0.42) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL11111474 0.74 KDM4E (0.40) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL8596411 0.74 INPPL1 (0.46) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL1821429 0.73 INPPL1 (0.47) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL28698904 0.73 ALDH1A1 (0.39) INPPL1INPP5AAKT1INPP5BSRC
SCHEMBL15811768 0.73 INPPL1 (0.49) INPPL1INPP5AAKT1INPP5BSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7723449-B2 Catalysts for synthesizing a polypropylene with a wide molecular weight distribution and use of the same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2010-05-25 US claimed
US-20090023881-A1 Catalyst for synthesizing a polypropylene with a wide molecular weight distribution and use of the same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2009-01-22 US claimed
US-7723449-B2 Catalysts for synthesizing a polypropylene with a wide molecular weight distribution and use of the same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2010-05-25 US disclosed
US-20090023881-A1 Catalyst for synthesizing a polypropylene with a wide molecular weight distribution and use of the same CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2009-01-22 US disclosed