Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL15139934 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| Bromide SCHEMBL8943360 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| Bromide SCHEMBL15139935 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| Bromide SCHEMBL328937 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| Bromide SCHEMBL9602026 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| Bromide SCHEMBL8943351 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| SCHEMBL8613971 | 0.94 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| SCHEMBL29012032 | 0.94 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| SCHEMBL2508249 | 0.94 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1LMNAKMT2A | |
| SCHEMBL157380 | 0.94 | ALDH1A1 (0.54) | ALDH1A1TSHRMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116324123-B | Hydrophobically modified associative thickener polymer and preparation method and application thereof | 赫尔克里士有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-116324124-B | Hydrophobically modified associative thickener polymer and preparation method and application thereof | 赫尔克里士有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-116324124-A | Hydrophobically modified associative thickener polymer and preparation method and application thereof | 赫尔克里士有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116324123-A | Hydrophobically modified associative thickener polymer and preparation method and application thereof | 赫尔克里士有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-115537961-B | Waterproof flame-retardant polyester fabric and preparation method thereof | 深圳市影儿服饰有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-115537961-A | Waterproof flame-retardant polyester fabric and preparation method thereof | 深圳市影儿服饰有限公司 | 2022-12-30 | — | — | CN | claimed |
| US-20200399428-A1 | SYSTEMS, METHODS AND HYDROGELS FOR CELL CULTURE AND ANALYSIS | PHENOMEX INC. (US) | 2020-12-24 | — | — | US | claimed |
| EP-3681935-A2 | SYSTEMS, METHODS AND HYDROGELS FOR CELL CULTURE AND ANALYSIS | Evorion Biotechnologies GmbH (DE) | 2020-07-22 | — | — | EP | claimed |
| WO-2019048714-A2 | SYSTEMS, METHODS AND HYDROGELS FOR CELL CULTURE AND ANALYSIS | EVORION BIOTECHNOLOGIES GMBH (DE) | 2019-03-14 | — | — | WO | claimed |
| EP-3027676-B1 | PROCESS FOR THE PREPARATION OF A POLYTHIOETHERSULFIDE | AKZO NOBEL CHEMICALS INT BV (NL) | 2017-10-25 | — | — | EP | claimed |
| US-9771457-B2 | Process for the preparation of a polythioethersulfide | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2017-09-26 | — | — | US | claimed |
| EP-3027676-A2 | PROCESS FOR THE PREPARATION OF A POLYTHIOETHERSULFIDE | Akzo Nobel Chemicals International B.V. (NL) | 2016-06-08 | — | — | EP | claimed |
| US-20160152775-A1 | Process for the Preparation of a Polyethersulfide | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2016-06-02 | — | — | US | claimed |
| WO-2015014876-A2 | PROCESS FOR THE PREPARATION OF A POLYTHIOETHERSULFIDE | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2015-02-05 | — | — | WO | claimed |
| JP-6072989-A | — | — | None | — | — | JP | disclosed |
| JP-11302359-A | — | — | None | — | — | JP | disclosed |
| US-12590181-B2 | Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof | HERCULES LLC (US) | 2026-03-31 | — | — | US | disclosed |
| US-4322491-A | BINDER, PHOTOINITIATOR, AND AN UNSATURATED COMPOUND | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |
| US-4311782-A | POLYETHER OF ORTHOCARBOXYLIC ESTER | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-19 | — | — | US | disclosed |
| US-4088495-A | Silver halide photographic element containing a gelatinous layer hardened with an aliphatic hydrocarbon having at least three vinylsulfonyl groups | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) | 1978-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12590181-B2 | Hydrophobically-modified associative thickener polymers process for the preparation and uses thereof | PHOSPHO1, H1-10, H1-0 | ALDH1A1 4014/4885TSHR 3461/4885MEN1 3872/4885 |
| US-20200399428-A1 | SYSTEMS, METHODS AND HYDROGELS FOR CELL CULTURE AND ANALYSIS | HLCS, CD63, CD44 | ALDH1A1 2430/4885TSHR 3770/4885MEN1 3566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.