SCHEMBL328948

SCHEMBL328948

C=CC=CC(C)C(=CC=Cc1ccccc1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.42
MCL1 Q07820 1/20 0.41
CYP3A4 P08684 1/20 0.40
CYP1A2 P05177 2/20 0.40
HPGD P15428 2/20 0.40
CYP2C9 P11712 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
LMNA P02545 4/20 0.37
MAOB P27338 3/20 0.37
TDP1 Q9NUW8 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9422272 0.89 CYP1A2 (0.40) GRIK1MCL1CYP3A4CYP1A2HPGD
SCHEMBL19205915 0.88 GRIK1 (0.46) GRIK1MCL1CYP3A4CYP1A2HPGD
SCHEMBL9507943 0.84 HDAC3 (0.47) GRIK1MCL1CYP3A4CYP1A2HPGD
SCHEMBL6705335 0.81 MCL1 (0.49) GRIK1MCL1CYP3A4CYP1A2HPGD
SCHEMBL10482273 0.78 AKR1C3 (0.45) GRIK1MCL1CYP3A4CYP1A2HPGD
SCHEMBL17274471 0.75 CYP3A4 (0.44) GRIK1CYP3A4CYP1A2CYP2C9HDAC3
SCHEMBL8211323 0.75 MCL1 (0.43) GRIK1MCL1CYP1A2HPGDCYP2C9
Styrene SCHEMBL3892960 0.75 ALDH1A1 (0.44) CYP3A4CYP1A2HPGDHDAC3HDAC4
Acetone SCHEMBL10911886 0.72 GLA (0.55) CYP3A4CYP1A2CYP2C9HDAC3HDAC4
Butadiene SCHEMBL9678114 0.72 AKR1C3 (0.52) GRIK1MCL1CYP3A4CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10010665-B2 Air separator for extracorporeal fluid treatment sets GAMBRO LUNDIA AB (SE) 2018-07-03 US disclosed
US-20140230657-A1 AIR SEPARATOR FOR EXTRACORPOREAL FLUID TREATMENT SETS GAMBRO LUNDIA AB (SE) 2014-08-21 US disclosed
US-8747342-B2 Air separator for extracorporeal fluid treatment sets GAMBRO LUNDIA AB (SE) 2014-06-10 US disclosed
EP-2407191-B1 Air separator extracorporeal fluid treatment sets GAMBRO LUNDIA AB (SE) 2012-12-12 EP disclosed
EP-2407191-A1 Air separator extracorporeal fluid treatment sets Gambro Lundia AB (SE) 2012-01-18 EP disclosed
EP-2081620-B1 AIR SEPARATOR FOR EXTRACORPOREAL FLUID TREATMENT SETS GAMBRO LUNDIA AB (SE) 2011-11-23 EP disclosed
US-20100292627-A1 AIR SEPARATOR FOR EXTRACORPOREAL FLUID TREATMENT SETS GAMBRO LUNDIA AB (SE) 2010-11-18 US disclosed
EP-2081620-A1 AIR SEPARATOR FOR EXTRACORPOREAL FLUID TREATMENT SETS Gambro Lundia AB (SE) 2009-07-29 EP disclosed
WO-2008053261-A1 AIR SEPARATOR FOR EXTRACORPOREAL FLUID TREATMENT SETS GAMBRO LUNDIA AB (SE) 2008-05-08 WO disclosed
WO-1990010296-A1 APPLICATIONS FOR GRAPHITE FIBRILS JAPAN SYNTHETIC RUBBER COMPANY, LTD. (JP) 1990-09-07 WO disclosed
EP-0010558-B1 HIGH IMPACT FIRE RETARDANT MONOVINYL AROMATIC RESIN COMPOSITION Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-02-16 EP disclosed
US-4219466-A BLENDS OF A MONOVINYL AROMATIC POLYMER, BUTADIENE-STYRENE BLOCK COPOLYMER, HALIDE FLAME RETARDANT COMPOUND, AND AN ANTIMONY COMPOUND; LOW CURRENT ELECTRICAL USES ASAHI-DOW LIMITED (JP) 1980-08-26 US disclosed
EP-0010558-A1 High impact fire retardant monovinyl aromatic resin composition Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1980-05-14 EP disclosed