SCHEMBL8211323

SCHEMBL8211323

CC(C=Cc1ccccc1)C(=CC=CC#N)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 3/20 0.43
CYP1A2 P05177 2/20 0.38
LMNA P02545 2/20 0.36
HTT P42858 2/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 3/20 0.35
GLA P06280 1/20 0.35
HDAC3 O15379 2/20 0.35
HDAC4 P56524 2/20 0.35
HDAC1 Q13547 2/20 0.35
HDAC7 Q8WUI4 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC10 Q969S8 2/20 0.35
HDAC11 Q96DB2 2/20 0.35
HDAC8 Q9BY41 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6705335 0.89 MCL1 (0.49) MCL1CYP1A2LMNAHTTHPGD
SCHEMBL19205915 0.86 GRIK1 (0.46) MCL1CYP1A2LMNAHTTHPGD
SCHEMBL9422272 0.81 CYP1A2 (0.40) MCL1CYP1A2LMNAHTTHPGD
SCHEMBL9507943 0.76 HDAC3 (0.47) MCL1CYP1A2LMNAHPGDKDM4E
SCHEMBL6471965 0.75 MCL1 (0.46) MCL1CYP1A2LMNAHTTHPGD
SCHEMBL328948 0.75 GRIK1 (0.42) MCL1CYP1A2LMNAHTTHPGD
SCHEMBL1258942 0.73 MCL1 (0.34) MCL1CYP1A2LMNAALDH1A1MAPT
SCHEMBL11576286 0.73 TDP1 (0.35) MCL1CYP1A2LMNAALDH1A1MAPT
Acrylonitrile SCHEMBL17443016 0.73 CYP1A2 (0.41) MCL1CYP1A2LMNAHTTHPGD
SCHEMBL123960 0.73 LMNA (0.46) MCL1CYP1A2LMNAHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4199491-A Polyolefin resin composition IDEMITSU KOSAN COMPANY LIMITED (JP) 1980-04-22 US claimed
US-6071489-A PREPARING A LITHIUM TRANSITION METAL OXIDE POWDER BY MIXING A LITHIUM SALT AND A TRANSITION METAL SALT WITH A CHELATING AGENT; FORMING A SOL; FORMING A GEL; CALCINING SAMSUNG DISPLAY DEVICE CO., LTD. (KR) 2000-06-06 US disclosed