SCHEMBL32895

SCHEMBL32895

NS(=O)(=O)c1cc2ccccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 1.00
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA9 Q16790 1/20 0.56
AOC3 Q16853 2/20 0.50
AKR1B1 P15121 1/20 0.50
DAO P14920 1/20 0.48
DDO Q99489 1/20 0.48
CNR1 P21554 3/20 0.48
LOXL2 Q9Y4K0 1/20 0.46
FLT3 P36888 1/20 0.46
CYP2A6 P11509 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32681985 1.00 CA2 (1.00) CA2CA12CA1CA9AOC3
SCHEMBL28568569 0.83 CA2 (0.71) CA2CA12CA1CA9AOC3
SCHEMBL329510 0.82 CA2 (0.69) CA2CA12CA1CA9AOC3
SCHEMBL28535223 0.81 CA2 (0.66) CA2CA12CA1CA9AOC3
SCHEMBL29560278 0.80 CA2 (0.67) CA2CA12CA1CA9AOC3
SCHEMBL5610313 0.80 CA2 (0.67) CA2CA12CA1CA9AOC3
SCHEMBL7014167 0.80 CA2 (0.67) CA2AOC3AKR1B1DAODDO
SCHEMBL516901 0.80 CA2 (0.67) CA2CA12CA1CA9AOC3
SCHEMBL517161 0.80 CA2 (0.67) CA2CA12CA1CA9AOC3
SCHEMBL30437414 0.79 CA2 (0.66) CA2CA12CA1CA9AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119497717-A Linker, conjugate and uses thereof 启德医药科技(苏州)有限公司 2025-02-21 CN claimed
CN-118251241-A Antibodies, linkers, supports, conjugates and uses thereof 启德医药科技(苏州)有限公司 2024-06-25 CN claimed
WO-2024002330-A1 IMMOBILIZED ENDOGLYCOSIDASE FUSION PROTEIN AND USE THEREOF 启德医药科技(苏州)有限公司 2024-01-04 WO claimed
WO-2023232144-A1 OLIGOSACCHARIDE LINKER, LINKER-SUPPORTED MATERIAL COMPRISING OLIGOSACCHARIDE LINKER, ANTIBODY-DRUG CONJUGATE HAVING SUGAR CHAIN REMODELING, PREPARATION METHOD THEREFOR AND USE THEREOF 启德医药科技(苏州)有限公司 2023-12-07 WO claimed
CN-117177775-A Linker, conjugate and uses thereof 启德医药科技(苏州)有限公司 2023-12-05 CN claimed
CN-116940236-A Composition containing benzylamine acaricide and application thereof 山东康乔生物科技有限公司 2023-10-24 CN claimed
CN-116917484-A Ligase fusion proteins and uses thereof 启德医药科技(苏州)有限公司 2023-10-20 CN claimed
CN-116874406-A Indolyl sulfonamide compound and preparation method and application thereof 山东大学 2023-10-13 CN claimed
CN-116784339-A Pesticide composition and application thereof 山东省联合农药工业有限公司 2023-09-22 CN claimed
CN-114395051-B Ligase fusion proteins and uses thereof 启德医药科技(苏州)有限公司 2023-06-30 CN claimed
CN-101434571-A Cycloalkano [1,2-b] indole sulfonic acid amide, and method for synthesizing isomer or salt thereof HANGZHOU RONGLI MEDICINE TECHN (CN) 2009-05-20 CN claimed
EP-1947085-A1 Substituted indole sulfonamide compounds, their preparation and use as medicaments Laboratorios del Dr. Esteve S.A. (ES) 2008-07-23 EP claimed
US-5374647-A Anticoagulants, thromboxane synthase inhibitors BAYER AKTIENGESELLSCHAFT (DE) 1994-12-20 US claimed
US-5204374-A Anticoagulants; thromboxane A2-antagonist; antiischemic agents; cardiovascular disorders; asthma; antiallergens BAYER AKTIENGESELLSCHAFT (DE) 1993-04-20 US claimed
CN-1070397-A Dihydropyridine and method for making and medicinal thereof that the indoles sulphonamide replaces BAYER AG (DE) 1993-03-31 CN claimed
EP-0533014-A1 Indolesulfonamide substituted dihydropyridines, process for their preparation and drugs containing them BAYER AG (DE) 1993-03-24 EP claimed
EP-0473024-A1 Heterocyclic substituted cycloalkano(b)-indolesulfonamides BAYER AG (DE) 1992-03-04 EP claimed
CN-1015711-B Cycloalkaho [1,2-b] indole-sulphonamides BAYER AG (DE) 1992-03-04 CN claimed
EP-0451634-A2 Cycloalkano[b]dihydroindoles and -indolesulphonamides substituted by heterocycles BAYER AG (DE) 1991-10-16 EP claimed
US-4965258-A Anticoagulant; thromboxane a2 antagonist BAYER AKTIENGESELLSCHAFT (DE) 1990-10-23 US claimed