SCHEMBL3289560

SCHEMBL3289560

CC(C)CC(NC(=O)C(N)C(C)C)C(=O)NC(CO)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 6/20 0.55
▸ ALDH1A1 P00352 2/20 0.46
▸ LAP3 P28838 3/20 0.44
▸ TGFBR1 P36897 3/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ LMNA P02545 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ MAPT P10636 1/20 0.41
▸ DPP4 P27487 1/20 0.41
▸ FAP Q12884 1/20 0.41
▸ DPP8 Q6V1X1 1/20 0.41
▸ DPP9 Q86TI2 1/20 0.41
▸ DPP7 Q9UHL4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31630525 1.00 MME (0.55) MMEALDH1A1LAP3TGFBR1MEN1
SCHEMBL3289576 1.00 MME (0.55) MMEALDH1A1LAP3TGFBR1MEN1
SCHEMBL30930167 0.94 MME (0.51) MMEALDH1A1LAP3MEN1LMNA
SCHEMBL31139354 0.92 ALDH1A1 (0.55) MMEALDH1A1LAP3MEN1LMNA
SCHEMBL31139320 0.92 ALDH1A1 (0.55) MMEALDH1A1LAP3MEN1LMNA
SCHEMBL31139330 0.92 ALDH1A1 (0.55) MMEALDH1A1LAP3MEN1LMNA
SCHEMBL29349631 0.92 ALDH1A1 (0.55) MMEALDH1A1LAP3MEN1LMNA
SCHEMBL31139360 0.92 ALDH1A1 (0.55) MMEALDH1A1LAP3MEN1LMNA
SCHEMBL29590449 0.90 MME (0.49) MMETGFBR1DPP4FAPDPP8
SCHEMBL29696989 0.90 MME (0.49) MMETGFBR1DPP4FAPDPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101948906-B Reagent with protease reaction promoter and/or pigment stabilizing agent ASAHI KASEI PHARMA CORP 2013-02-27 — — CN disclosed
CN-101948906-A The reagent that contains protease reaction promoter and/or colorant stabilizer ASAHI KASEI PHARMA CORP 2011-01-19 — — CN disclosed
CN-101023168-B Reagent containing protease reaction promoter and/or pigment stabilizer ASAHI KASEI PHARMA CORP 2010-10-13 — — CN disclosed
US-7718437-B2 Method for analyzing N-terminal protein adducts ADDUCT ANALYS AB (SE) 2010-05-18 — — US disclosed
EP-1738177-B1 METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS ADDUCT ANALYS AB (SE) 2009-02-11 — — EP disclosed
US-20070224685-A1 Reagent Containing Protease Reaction Promoter and/or Colorant Stabilizer ASAHI KASEI PHARMA CORPORATION (JP) 2007-09-27 — — US disclosed
CN-101023168-A Reagent containing protease reaction promoter and/or pigment stabilizer ASAHI KASEI PHARMA CORP (JP) 2007-08-22 — — CN disclosed
US-20070190659-A1 Method for analyzing n-terminal protein adducts ADDUCT ANALYS AB (SE) 2007-08-16 — — US disclosed
EP-1788081-A1 REAGENT CONTAINING PROTEASE REACTION PROMOTER AND/OR COLORANT STABILIZER Asahi Kasei Pharma Corporation (JP) 2007-05-23 — — EP disclosed
EP-1738177-A1 METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS Adduct Analys AB (SE) 2007-01-03 — — EP disclosed
WO-2005101020-A1 METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS ADDUCT ANALYS AB (SE) 2005-10-27 — — WO disclosed
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