SCHEMBL29696989

SCHEMBL29696989

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nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 6/20 0.49
▸ TGFBR1 P36897 3/20 0.49
▸ DPP4 P27487 2/20 0.46
▸ DPP8 Q6V1X1 2/20 0.46
▸ DPP9 Q86TI2 2/20 0.46
▸ DPP7 Q9UHL4 2/20 0.46
▸ FAP Q12884 1/20 0.46
▸ SLC7A5 Q01650 1/20 0.43
▸ ECE1 P42892 2/20 0.41
▸ ACE P12821 1/20 0.41
▸ CA2 P00918 2/20 0.36
▸ CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29590449 1.00 MME (0.49) MMETGFBR1DPP4DPP8DPP9
SCHEMBL29868562 1.00 MME (0.49) MMETGFBR1DPP4DPP8DPP9
SCHEMBL29630533 1.00 MME (0.49) MMETGFBR1DPP4DPP8DPP9
SCHEMBL6674368 0.96 TGFBR1 (0.52) MMETGFBR1DPP4DPP8DPP9
SCHEMBL28124001 0.96 TGFBR1 (0.52) MMETGFBR1DPP4DPP8DPP9
SCHEMBL31630525 0.90 MME (0.55) MMETGFBR1DPP4DPP8DPP9
SCHEMBL3289560 0.90 MME (0.55) MMETGFBR1DPP4DPP8DPP9
SCHEMBL3289576 0.90 MME (0.55) MMETGFBR1DPP4DPP8DPP9
SCHEMBL30930167 0.90 MME (0.51) MMEDPP4DPP8DPP9DPP7
SCHEMBL29462928 0.90 DPP4 (0.43) MMETGFBR1DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2025-01-09 — — US disclosed
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF ENTRADA THERAPEUTICS, INC. 2022-06-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011367-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 MME 286/4885TGFBR1 4721/4885DPP4 891/4885
US-20220177523-A1 CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF VIP, LNPEP, TAP1 MME 286/4885TGFBR1 4721/4885DPP4 891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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