⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19460972 | 1.00 | — | — | |
| Water SCHEMBL5134268 | 0.97 | TP53 (0.46) | — | |
| SCHEMBL28239279 | 0.97 | TP53 (0.46) | — | |
| SCHEMBL14955034 | 0.85 | TP53 (0.42) | — | |
| SCHEMBL329737 | 0.84 | TP53 (0.56) | — | |
| SCHEMBL27987417 | 0.83 | TP53 (0.37) | — | |
| SCHEMBL28033097 | 0.82 | TP53 (0.54) | — | |
| Hydrochloric Acid SCHEMBL28075551 | 0.82 | TP53 (0.54) | — | |
| SCHEMBL692235 | 0.82 | TP53 (0.65) | — | |
| SCHEMBL8497172 | 0.80 | TP53 (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158403-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-16 | — | — | US | claimed |
| CN-117680097-A | Carbon dioxide absorbent and preparation method thereof | 西安建筑科技大学 | 2024-03-12 | — | — | CN | claimed |
| CN-115178058-A | Method for absorbing and separating ammonia-containing gas by adopting supergravity enhanced ionic liquid | 南京澳博工业智能科技研究院有限公司 | 2022-10-14 | — | — | CN | claimed |
| US-20220135573-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-05-05 | — | — | US | claimed |
| US-20170349595-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND ABL AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2017-12-07 | — | — | US | claimed |
| EP-2501236-B1 | N-[2-fluoro-3-(4-amino-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)-phenyl]-4-benzenesulfonamide derivatives as Raf protein kinase modulators for the treatment of cancer | PLEXXIKON INC (US) | 2017-03-29 | — | — | EP | claimed |
| EP-2222162-B1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | DANA FARBER CANCER INST INC (US) | 2016-11-16 | — | — | EP | claimed |
| US-20150094275-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2015-04-02 | — | — | US | claimed |
| US-20110312908-A1 | SMALL MOLECULE MYRISTATE INHIBITORS OF BCR-ABL AND METHODS OF USE | THE SCRIPPS RESEARCH INSTITUTE | 2011-12-22 | — | — | US | claimed |
| CN-101702038-B | Resin lens with high impact resistance | JIANGYIN MAOSHENG OPTICAL MATERIAL CO LTD | 2011-05-11 | — | — | CN | claimed |
| CN-101702039-B | Resin lens with high impact resistance | JIANGYIN MAOSHENG OPTICAL MATERIAL CO LTD | 2011-02-09 | — | — | CN | claimed |
| CN-101712743-A | Solution of isocyanato group containing terminated polythiourethane prepolymer and preparation method thereof | JIANGYIN CITY MAOSHENG OPTICAL | 2010-05-26 | — | — | CN | claimed |
| CN-101712742-A | Solution of sulfhydryl-containing terminated polythiourethane prepolymer and preparation method thereof | JIANGYIN CITY MAOSHENG OPTICAL | 2010-05-26 | — | — | CN | claimed |
| CN-101702039-A | Resin lens with high impact resistance | JIANXING ZHANG | 2010-05-05 | — | — | CN | claimed |
| CN-101702038-A | Resin lens with high impact resistance | JIANXING ZHANG | 2010-05-05 | — | — | CN | claimed |
| EP-1824827-B1 | METHOD FOR PRODUCING ONIUM SALTS COMPRISING ALKYL ANIONS OR ARYL SULFONATE ANIONS OR ALKYL ANIONS OR ARYL CARBOXYLATE ANIONS HAVING A LOW HALIDE CONTENT | MERCK PATENT GMBH (DE) | 2008-09-17 | — | — | EP | claimed |
| CN-101223186-A | Process for the preparation of 3-oxo-pregn-4-en-21, 17-olides by metal-free oxidation of 17- (3-hydroxypropyl) -3, 17-dihydroxyandrostanes | BAYER SCHERING PHARMA AG (DE) | 2008-07-16 | — | — | CN | claimed |
| EP-1394607-B1 | Homogeneous single-part color developer concentrate for color film processing and method of using same | EASTMAN KODAK CO (US) | 2006-03-01 | — | — | EP | claimed |
| EP-1394607-A1 | Homogeneous single-part color developer concentrate for color film processing and method of using same | EASTMAN KODAK COMPANY (US) | 2004-03-03 | — | — | EP | claimed |
| US-6664036-B1 | N,N-Dialkyl-p-phenylenediamine; N,N-dialkyl- or diarylhydroxylamine, and charged cosolvent; color negative or reversal photographic silver halide films | EASTMAN KODAK COMPANY | 2003-12-16 | — | — | US | claimed |