SCHEMBL329216

SCHEMBL329216

COC(=O)[CH]CC(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
HCAR2 Q8TDS4 2/20 0.46
KEAP1 Q14145 1/20 0.46
NFE2L2 Q16236 1/20 0.46
GAA P10253 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MGAM O43451 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
TET2 Q6N021 1/20 0.34
LMNA P02545 3/20 0.34
ALDH1A1 P00352 3/20 0.34
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
MAPT P10636 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5835931 0.81 MGAM (0.46) TSHRHCAR2GAAHSD17B10MGAM
SCHEMBL11066780 0.81 GAA (0.52) HCAR2KEAP1NFE2L2GAAHSD17B10
SCHEMBL2654703 0.80 DGAT1 (0.39) TSHRHCAR2KEAP1NFE2L2CA12
SCHEMBL6949768 0.79
SCHEMBL6945786 0.79
SCHEMBL195981 0.78
SCHEMBL11004334 0.76
SCHEMBL29470046 0.76
SCHEMBL28355601 0.76
SCHEMBL212257 0.75 HCAR2 (0.55) TSHRHCAR2KEAP1NFE2L2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-B1 HERBICIDAL AND FUNGICIDAL 3-PHENYLISOXAZOLIN DERIVATIVES BAYER CROPSCIENCE AG (DE) 2019-08-21 EP claimed
US-20150245615-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION BAYER CROPSCIENCE AG (DE) 2015-09-03 US claimed
US-7858802-B2 Method of preparing ionic liquids BASF SE (DE) 2010-12-28 US claimed
US-20080214536-A1 Amido-Substituted 6-Phenylphenanthridines NYCOMED GMBH (DE) 2008-09-04 US claimed
US-20070185149-A1 Novel amido-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibtors ALTANA PHARMA AG (DE) 2007-08-09 US claimed
EP-0188805-B1 1,3-DITHIOLE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-09-06 EP claimed
EP-0188805-A1 1,3-Dithiole derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 1986-07-30 EP claimed
US-20240240095-A1 NEW COMPOSITIONS FOR REDUCING CRYSTALLIZATION OF PARAFFIN CRYSTALS IN FUELS BASF SE (DE) 2024-07-18 US disclosed
WO-2024149635-A1 BRANCHED AMINES AS ADDITIVES FOR GASOLINE FUELS BASF SE (DE) 2024-07-18 WO disclosed
US-20240217923-A1 A DIISOCYANATE STABILIZER, USE THEREOF, AND DIISOCYANATE COMPOSITION BASF (CHINA) COMPANY LIMITED (CN) 2024-07-04 US disclosed
EP-4382588-A1 ADDITIVES FOR IMPROVING THERMAL STABILITY OF FUELS BASF SE (DE) 2024-06-12 EP disclosed
CN-118119688-A Reduction of asphaltenes from marine fuels 巴斯夫欧洲公司 2024-05-31 CN disclosed
CN-118119689-A Reduction of asphaltenes from marine fuels 巴斯夫欧洲公司 2024-05-31 CN disclosed
US-5025048-A Oxygen resistant, storage-stable curable polysiloxanes hydrosilated by a polycyclic polyene and a compound containing an amine and a hydroxy, both sterically hindered HERCULES INCORPORATED (US) 1991-06-18 US disclosed
EP-0413657-A2 Mono- and diacyl phosphine oxides CIBA-GEIGY AG (CH) 1991-02-20 EP disclosed
EP-0360747-A2 Telomeric compound FMC CORPORATION (UK) LIMITED (GB) 1990-03-28 EP disclosed
US-4211696-A Disperse monoazo dyestuffs derived from 3,5-dinitro-2-amino thiophene as disazo component and an arylamine coupling component IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-07-08 US disclosed
US-4198334-A HEAT, LIGHT, OXIDATION RESISTANCE, PLASTICS CIBA-GEIGY CORPORATION (US) 1980-04-15 US disclosed
EP-0009191-A1 Water-insoluble disazodyestuffs, their preparation and application CASSELLA Aktiengesellschaft (DE) 1980-04-02 EP disclosed
US-4013632-A SYNTHETIC FIBERS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240217923-A1 A DIISOCYANATE STABILIZER, USE THEREOF, AND DIISOCYANATE COMPOSITION TST, DDT, PAH TSHR 2772/4885HCAR2 3648/4885KEAP1 1104/4885
US-20070185149-A1 Novel amido-substituted hydroxy-6-phenylphenanthridines and their use as pde4 inhibtors PDE4A, PDE4B, PDE4C TSHR 1574/4885HCAR2 1352/4885KEAP1 3918/4885
US-20080214536-A1 Amido-Substituted 6-Phenylphenanthridines PDE4A, PDE4B, PDE3A TSHR 1041/4885HCAR2 2382/4885KEAP1 3749/4885
US-20150245615-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION CYP4X1, CBR3, PAOX TSHR 1336/4885HCAR2 345/4885KEAP1 1420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.