Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | CPT1A | P50416 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31587305 | 0.99 | CCR3 (0.72) | CCR3HDAC1PIK3CDPIK3CBFPR2 | |
| SCHEMBL13351459 | 0.87 | CCR3 (0.74) | CCR3HDAC1PIK3CDPIK3CBCPT1A | |
| SCHEMBL13351509 | 0.87 | CCR3 (0.74) | CCR3HDAC1PIK3CDPIK3CBCPT1A | |
| SCHEMBL5393280 | 0.85 | CCR3 (1.00) | CCR3HDAC1PIK3CDPIK3CBCPT1A | |
| SCHEMBL13351530 | 0.85 | CCR3 (0.71) | CCR3HDAC1PIK3CDPIK3CBCPT1A | |
| Hydrochloric Acid SCHEMBL31587373 | 0.82 | CCR3 (0.62) | CCR3CYP11B1CYP11B2HTTSMN1; SMN2 | |
| SCHEMBL13319170 | 0.81 | CCR3 (0.60) | CCR3HDAC1CPT1ACYP11B1CYP11B2 | |
| SCHEMBL3291520 | 0.81 | TP53 (0.49) | CCR3HDAC1FPR2KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL3289617 | 0.80 | TP53 (0.48) | CCR3HDAC1FPR2KDM4EALDH1A1 | |
| SCHEMBL23946257 | 0.80 | CYP11B2 (0.58) | CCR3CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723360-B2 | Alkyl-and piperidine-substituted benzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723360-B2 | Alkyl-and piperidine-substituted benzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723360-B2 | Alkyl-and piperidine-substituted benzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| EP-1776356-B1 | ALKYL-AND PIPERIDINE-SUBSTITUTED BENZIMIDAZOLE-DERIVATES | BOEHRINGER INGELHEIM INT (DE) | 2008-09-17 | — | — | EP | disclosed |
| EP-1776356-B1 | ALKYL-AND PIPERIDINE-SUBSTITUTED BENZIMIDAZOLE-DERIVATES | BOEHRINGER INGELHEIM INT (DE) | 2008-09-17 | — | — | EP | disclosed |
| EP-1776356-A1 | ALKYL-AND PIPERIDINE-SUBSTITUTED BENZIMIDAZOLE-DERIVATES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006013073-A1 | ALKYL-AND PIPERIDINE-SUBSTITUTED BENZIMIDAZOLE-DERIVATES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-02-09 | — | — | WO | disclosed |
| US-20060030590-A1 | Alkyl-and piperidine-substituted benzimidazole derivatives | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030590-A1 | Alkyl-and piperidine-substituted benzimidazole derivatives | ABCB11, KCNJ11, ABCB1 | CCR3 2279/4885HDAC1 229/4885PIK3CD 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.