Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293150 | 1.00 | MAPT (0.46) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL3290509 | 0.84 | ALDH1A1 (0.54) | MAPTL3MBTL1MEN1KMT2AMAPK1 | |
| SCHEMBL155459 | 0.84 | MAPT (0.46) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL113257 | 0.84 | MAPT (0.46) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL3290659 | 0.81 | CYP2C9 (0.47) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL1455254 | 0.73 | ALDH1A1 (0.41) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL1455249 | 0.73 | ALDH1A1 (0.41) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL1455251 | 0.73 | ALDH1A1 (0.41) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL904520 | 0.73 | MAPT (0.38) | MAPTRAB9ACASP3SENP8SENP7 | |
| SCHEMBL10415825 | 0.70 | ALDH1A1 (0.57) | MAPTRAB9ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |