Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PRF1 | P14222 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | PKMYT1 | Q99640 | 3/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | MYT1 | Q01538 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28414034 | 0.80 | DHODH (0.35) | KMT2AMAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL15112010 | 0.80 | KMT2A (0.40) | KMT2AALDH1A1MEN1PRF1PDGFRB | |
| Hydrochloric Acid SCHEMBL28791312 | 0.79 | KMT2A (0.39) | KMT2AALDH1A1MEN1PRF1PDGFRB | |
| SCHEMBL28995653 | 0.73 | KDM4E (0.35) | KMT2AMAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL28411172 | 0.72 | RAB9A (0.37) | KMT2AMAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL14301805 | 0.71 | CYP1A2 (0.44) | KMT2AMAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL20740807 | 0.69 | DAO (0.34) | ALDH1A1SMN1; SMN2HSD17B10KDM4EDAO | |
| SCHEMBL30241135 | 0.66 | PTGDR2 (0.40) | KMT2AALDH1A1MEN1HSD17B10PRF1 | |
| SCHEMBL28226825 | 0.66 | PARP1 (0.42) | KMT2AMAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL28566639 | 0.65 | CLK4 (0.42) | KMT2AMAPTRAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723321-B2 | Chromane substituted benzimidazole derivatives | RAQUALIA PHARMA INC. (JP) | 2010-05-25 | — | — | US | disclosed |
| US-20070142448-A1 | Chromane Substituted Benzimidazole Derivatives | PFIZER INC. | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142448-A1 | Chromane Substituted Benzimidazole Derivatives | HRH2, HRH4, HRH1 | KMT2A 4385/4885MAPT 4806/4885RAB9A 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.