Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6643409 | 0.82 | NOS2 (0.41) | KDM4EMAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL14301805 | 0.78 | CYP1A2 (0.44) | KDM4EMAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL5144295 | 0.76 | TLR8 (0.44) | KDM4EALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL3294049 | 0.73 | KMT2A (0.35) | KDM4EMAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL28566639 | 0.71 | CLK4 (0.42) | KDM4EMAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL15174271 | 0.71 | RPS6KA5 (0.41) | KDM4EALDH1A1RAB9AEGFRGAA | |
| SCHEMBL16739927 | 0.70 | NOS3 (0.31) | ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL5146857 | 0.69 | CYP11B2 (0.40) | KDM4EMAPTMAPK1ALDH1A1RAB9A | |
| SCHEMBL5145732 | 0.69 | NR1H2 (0.41) | KDM4EALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL23459658 | 0.67 | RPS6KA3 (0.38) | KDM4EALDH1A1RAB9AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057045-A | Fibroblast growth factor receptor kinase inhibitors | 金耐特生物制药公司 | 2023-05-02 | — | — | CN | disclosed |