Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4378454 | 0.92 | HTT (0.61) | HTTCYP19A1MAPTTDP1ALDH1A1 | |
| SCHEMBL4800134 | 0.91 | CYP19A1 (0.61) | HTTCYP19A1MAPTTDP1ALDH1A1 | |
| SCHEMBL11216634 | 0.90 | HTT (0.66) | HTTCYP19A1MAPTTDP1ALDH1A1 | |
| SCHEMBL3296474 | 0.89 | CYP19A1 (0.63) | HTTCYP19A1MAPTTDP1ALDH1A1 | |
| SCHEMBL3293148 | 0.89 | CYP19A1 (0.63) | HTTCYP19A1MAPTTDP1ALDH1A1 | |
| SCHEMBL10339898 | 0.89 | CYP19A1 (0.63) | HTTCYP19A1MAPTTDP1ALDH1A1 | |
| SCHEMBL397794 | 0.89 | TDP1 (0.64) | HTTCYP19A1MAPTTDP1ALDH1A1 | |
| SCHEMBL29469600 | 0.89 | TDP1 (0.64) | HTTCYP19A1MAPTTDP1ALDH1A1 | |
| SCHEMBL11220203 | 0.88 | HTT (0.64) | HTTCYP19A1MAPTTDP1ALDH1A1 | |
| SCHEMBL11220987 | 0.88 | HTT (0.64) | HTTCYP19A1MAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741520-B2 | Sulfonanilide analogs as selective aromatase modulators (SAMs) | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-06-22 | — | — | US | disclosed |
| EP-1411090-B1 | Monoazo reactive red dyestuff | EVERLIGHT USA INC (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-1984325-A2 | SULFONANILIDE ANALOGS AS SELECTIVE AROMATASE MODULATORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2008-10-29 | — | — | EP | disclosed |
| US-20080045598-A1 | Novel sulfonanilide analogs as selective aromatase modulators (SAMs) | THE OHIO STATE UNIVERSITY (US) | 2008-02-21 | — | — | US | disclosed |
| WO-2007120379-A2 | SULFONANILIDE ANALOGS AS SELECTIVE AROMATASE MODULATORS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-10-25 | — | — | WO | disclosed |
| CN-1257233-C | Monoazo Reactive Red Dye | EVERLIGHT CHEM IND CORP (CN) | 2006-05-24 | — | — | CN | disclosed |
| US-6815536-B2 | DYESTUFFS FOR DYEING AND PRINTING OF MATERIALS CONTAINING EITHER CELLULOSE FIBERS, SUCH AS COTTON, ARTIFICIAL COTTON, LINEN, AND ARTIFICIAL LINEN, OR SYNTHETIC POLYAMIDE, SUCH AS WOOL, SILK, AND NYLON ETC. | EVERLIGHT USA, INC. | 2004-11-09 | — | — | US | disclosed |
| US-20040087780-A1 | Monoazo reactive red dyestuff | EVERLIGHT USA, INC. | 2004-05-06 | — | — | US | disclosed |
| CN-1493623-A | Monoazo Reactive Red Dye | 台湾永光化学工业股份有限公司 | 2004-05-05 | — | — | CN | disclosed |
| EP-1411090-A1 | Monoazo reactive red dyestuff | Everlight USA, Inc. (US) | 2004-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045598-A1 | Novel sulfonanilide analogs as selective aromatase modulators (SAMs) | CYP19A1, AR, SULT2A1 | HTT 3747/4885CYP19A1 1/4885MAPT 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.