SCHEMBL3294354

SCHEMBL3294354

ClCc1cc(CCl)c2ccccc2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.50
MAOA P21397 2/20 0.43
MAOB P27338 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 5/20 0.39
ALDH1A1 P00352 3/20 0.39
HPGD P15428 3/20 0.39
GLA P06280 2/20 0.39
CASP1 P29466 2/20 0.39
CASP7 P55210 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HSD17B10 Q99714 2/20 0.39
CHRM2 P08172 1/20 0.39
ADRA2A P08913 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
CHRM1 P11229 1/20 0.39
NQO2 P16083 1/20 0.39
DRD1 P21728 1/20 0.39
ACHE P22303 1/20 0.39
SLC6A2 P23975 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8357609 0.87 KMT2A (0.46) KMT2AMAOAMAOBL3MBTL1KDM4E
SCHEMBL11940531 0.83 KMT2A (0.50) KMT2AMAOAMAOBL3MBTL1KDM4E
SCHEMBL6089983 0.82 KMT2A (0.48) KMT2AMAOAMAOBL3MBTL1KDM4E
SCHEMBL11343689 0.82 KMT2A (0.53) KMT2AMAOAMAOBL3MBTL1KDM4E
SCHEMBL30517871 0.82 KMT2A (0.53) KMT2AMAOAMAOBL3MBTL1KDM4E
SCHEMBL8430983 0.81 NCF1 (0.55) KMT2AMAOAMAOBL3MBTL1KDM4E
SCHEMBL4848307 0.81 CYP1A2 (0.58) KMT2AL3MBTL1KDM4EALDH1A1HPGD
Hydrochloric Acid SCHEMBL6629225 0.80 KMT2A (0.52) KMT2AMAOAMAOBL3MBTL1KDM4E
SCHEMBL10523072 0.79 ACACA (0.46) KMT2AL3MBTL1KDM4EALDH1A1HPGD
SCHEMBL994597 0.78 CYP1A2 (0.60) KMT2AKDM4EALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732540-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-20090018012-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
WO-2002026713-A1 ANTIPARASITIC COMPOUNDS KING'S COLLEGE LONDON (GB) 2002-04-04 WO disclosed