SCHEMBL3294369

SCHEMBL3294369

CCCCCC(C)(C)Oc1ccc([SiH](O[SiH](c2ccc(OC(C)(C)CCCCC)cc2)c2ccc(OC(C)(C)CCCCC)cc2)c2ccc(OC(C)(C)CCCCC)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 6/20 0.33
S1PR4 O95977 4/20 0.33
S1PR3 Q99500 4/20 0.33
S1PR5 Q9H228 3/20 0.33
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
NR5A1 Q13285 1/20 0.32
SPHK2 Q9NRA0 1/20 0.31
TNNC1 P63316 5/20 0.31
SGPL1 O95470 1/20 0.31
GPR183 P32249 1/20 0.31
CERS2 Q96G23 1/20 0.31
PLA2G4B P0C869 1/20 0.31
LTA4H P09960 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3301785 0.85 CNR2 (0.31) TP53TSHRCNR1CNR2
SCHEMBL3298055 0.83 PPARA (0.39) TSHRCNR1CNR2
SCHEMBL3296586 0.80 CNR2 (0.33) S1PR1S1PR4S1PR3S1PR5TP53
SCHEMBL3294266 0.80 CNR2 (0.34) CNR1CNR2
SCHEMBL9345890 0.79 CNR2 (0.35) S1PR1S1PR4S1PR3S1PR5NR5A1
SCHEMBL3299249 0.79 KDM4E (0.32) S1PR1S1PR4S1PR3S1PR5TP53
SCHEMBL1454452 0.79 LTA4H (0.46) LTA4HCNR1CNR2
SCHEMBL3299388 0.78 CNR2 (0.50) CNR1CNR2
SCHEMBL5353479 0.78 TP53 (0.36) S1PR1S1PR4S1PR3S1PR5TP53
SCHEMBL5495925 0.78 TP53 (0.58) TP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741393-B2 Organic silicon-based compound and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same ARSA, OR10J3, HDAC10 S1PR1 338/4885S1PR4 584/4885S1PR3 390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.