SCHEMBL3294686

SCHEMBL3294686

CCN1C(=O)OC(C)(C)c2cc(C)c(-c3cc(C4CC4C(=O)O)ccc3OC(F)(F)F)cc21

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RXRA P19793 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13328337 1.00 RXRA (0.76) RXRA
SCHEMBL13328363 1.00 RXRA (0.76) RXRA
SCHEMBL3295672 0.92 RXRA (0.64) RXRA
SCHEMBL11957053 0.86 RXRA (1.00) RXRA
SCHEMBL3290402 0.86 RXRA (1.00) RXRA
SCHEMBL11957067 0.86 RXRA (1.00) RXRA
SCHEMBL11957059 0.86 RXRA (1.00) RXRA
SCHEMBL11957046 0.86 RXRA (1.00) RXRA
SCHEMBL13328368 0.86 RXRA (0.69) RXRA
SCHEMBL3292526 0.86 RXRA (0.69) RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313923-A1 METHOD FOR EXTRACTING ALCOHOLS FROM AN INITIAL MIXTURE COMPRISING ALCOHOLS IN AQUEOUS PHASE IFP Energies nouvelles (FR) 2024-02-07 EP claimed
CN-108636453-B Nano noble metal catalyst packaged by metal organic framework material and preparation method and application thereof 浙江工业大学 2020-11-13 CN disclosed
US-7723371-B2 Microbiocides SYNGENTA CROP PROTECTION, INC. (US) 2010-05-25 US disclosed
US-7723326-B2 Heterocyclic amide derivatives as RXR agonists for the treatment of dyslipidemia, hypercholesterolemia and diabetes JANSSEN PHARMACEUTICA N.V. (US) 2010-05-25 US disclosed
US-20090054496-A1 MICROBIOCIDES SYNGENTA CROP PROTECTION, INC. (US) 2009-02-26 US disclosed
EP-1956909-A1 MICROBIOCIDES Syngeta Participations AG (CH) 2008-08-20 EP disclosed
WO-2007057139-A1 MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-05-24 WO disclosed
US-20070078129-A1 Heterocyclic amide derivatives as RXR agonists for the treatment of dyslipidemia, hypercholesterolemia and diabetes JANSSEN PHARMACEUTICA N.V. 2007-04-05 US disclosed
US-3985754-A Para-fluorobenzoylpropyl-N-heterocyclic substituted quaternary salts AMERICAN CYANAMID COMPANY (US) 1976-10-12 US disclosed
US-3966748-A NEUROLEPTIC, ANALGESIC AMERICAN CYANAMID COMPANY (US) 1976-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054496-A1 MICROBIOCIDES CBR3, CBR1, HDHD5 RXRA 2747/4885
US-20070078129-A1 Heterocyclic amide derivatives as RXR agonists for the treatment of dyslipidemia, hypercholesterolemia and diabetes NR1H2, NR1H3, RXRA RXRA 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.