Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295309 | 1.00 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2TAS1R3TAS1R1 | |
| SCHEMBL13296122 | 1.00 | HCAR2 (0.50) | HCAR2KEAP1NFE2L2TAS1R3TAS1R1 | |
| SCHEMBL3294574 | 0.80 | ALDH1A1 (0.63) | HCAR2TAS1R3TAS1R1MMP1MMP2 | |
| SCHEMBL13296121 | 0.80 | ALDH1A1 (0.63) | HCAR2TAS1R3TAS1R1MMP1MMP2 | |
| SCHEMBL3294577 | 0.80 | ALDH1A1 (0.63) | HCAR2TAS1R3TAS1R1MMP1MMP2 | |
| SCHEMBL13296114 | 0.79 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2TAS1R3TAS1R1 | |
| SCHEMBL21559558 | 0.78 | TAS1R3 (0.45) | TAS1R3TAS1R1MMP1MMP2MMP3 | |
| SCHEMBL20450459 | 0.78 | TAS1R3 (0.47) | TAS1R3TAS1R1MMP1MMP2MMP3 | |
| SCHEMBL23470216 | 0.78 | TAS1R3 (0.43) | TAS1R3TAS1R1MMP1MMP2MMP3 | |
| SCHEMBL17688555 | 0.74 | HCAR2 (0.52) | HCAR2KEAP1NFE2L2GFPT1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732018-B2 | Durable coating compositions containing novel aspartic amine compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-08 | — | — | US | disclosed |
| EP-1833783-B1 | DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS | DU PONT (US) | 2009-04-15 | — | — | EP | disclosed |
| US-7449242-B2 | Durable coating compositions containing novel aspartic amine compounds | E.I. DU PONT DE NEMOURS & COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| EP-1833783-A1 | DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-09-19 | — | — | EP | disclosed |
| US-7166748-B2 | Durable coating compositions containing novel aspartic amine compounds | E.I. DUPONT DE NEMOURS & CO. (US) | 2007-01-23 | — | — | US | disclosed |
| US-20060228563-A1 | Durable coating compositions containing novel aspartic amine compounds | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-10-12 | — | — | US | disclosed |
| US-20060155056-A1 | Durable coating compositions containing novel aspartic amine compunds | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-07-13 | — | — | US | disclosed |
| US-20060155149-A1 | Durable coating compositions containing novel aspartic amine compounds | AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) | 2006-07-13 | — | — | US | disclosed |
| WO-2006066031-A1 | DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060155149-A1 | Durable coating compositions containing novel aspartic amine compounds | H1-10, H1-0, H1-5 | HCAR2 1539/4885KEAP1 2790/4885NFE2L2 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.