Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | PAM | P19021 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295683 | 1.00 | MMP1 (0.54) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL9762368 | 0.85 | IDO1 (0.57) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL3324115 | 0.85 | IDO1 (0.57) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL293067 | 0.85 | IDO1 (0.57) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL293068 | 0.85 | IDO1 (0.57) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL9595675 | 0.83 | MMP1 (0.55) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL9595673 | 0.83 | MMP1 (0.55) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL5547303 | 0.83 | MMP1 (0.49) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL10731136 | 0.82 | MMP1 (0.51) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL10731142 | 0.82 | MMP1 (0.51) | MMP1MMP2MMP9MMP12IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627832-A | Preparation method for synthesizing tenofovir alafenamide by oxidation method | 江西农业大学 | 2019-12-31 | — | — | CN | claimed |
| US-5187306-A | Reacting unsaturated amides with metallic bases to form metal salts, which are reacted with halogenated formic acid esters | NIPPON PAINT CO., LTD. (JP) | 1993-02-16 | — | — | US | claimed |
| CN-110627832-A | Preparation method for synthesizing tenofovir alafenamide by oxidation method | 江西农业大学 | 2019-12-31 | — | — | CN | disclosed |
| US-7727434-B2 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070039874-A1 | Membranes and methods of treating membranes | GENERAL ELECTRIC COMPANY | 2007-02-22 | — | — | US | disclosed |
| US-5434296-A | Reacting carbamate with metallic base to form salt; reacting with unsaturated acid halide to acylate | NIPPON PAINT CO., LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0465162-B1 | Process for producing unsaturated carbamic acid esters | NIPPON PAINT CO LTD (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-5187306-A | Reacting unsaturated amides with metallic bases to form metal salts, which are reacted with halogenated formic acid esters | NIPPON PAINT CO., LTD. (JP) | 1993-02-16 | — | — | US | disclosed |
| EP-0465162-A1 | Process for producing unsaturated carbamic acid esters | NIPPON PAINT CO., LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0095294-A1 | Deoxyuridine compounds, methods for preparing them and their use in medicine | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |