Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3294491 | 0.84 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19TLR8CYP19A1 | |
| SCHEMBL3297503 | 0.84 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19TLR8CYP19A1 | |
| SCHEMBL3297921 | 0.83 | CYP1A2 (0.45) | CYP1A2CYP2C9CYP2C19TLR8LTA4H | |
| SCHEMBL3298061 | 0.82 | ALDH1A1 (0.50) | CYP1A2CYP2C19TLR8KMT2AMAPT | |
| SCHEMBL3300356 | 0.80 | CYP1A2 (0.42) | CYP1A2CYP2C9CYP2C19TLR8LTA4H | |
| SCHEMBL3295598 | 0.80 | LTA4H (0.44) | CYP1A2CYP2C9CYP2C19TLR8LTA4H | |
| 1,2-Dibutoxybenzene SCHEMBL1226749 | 0.80 | CYP1A2 (0.72) | CYP1A2CYP2C9CYP2C19TLR8LTA4H | |
| 1,2-Dibutoxybenzene SCHEMBL29428927 | 0.80 | CYP1A2 (0.72) | CYP1A2CYP2C9CYP2C19TLR8LTA4H | |
| SCHEMBL3297756 | 0.79 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19TLR8LTA4H | |
| SCHEMBL3295354 | 0.79 | LTA4H (0.43) | CYP1A2CYP2C9CYP2C19TLR8LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741393-B2 | Organic silicon-based compound and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-22 | — | — | US | disclosed |
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | ARSA, OR10J3, HDAC10 | CYP1A2 945/4885CYP2C9 1864/4885CYP2C19 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.