SCHEMBL3296279

SCHEMBL3296279

O=S(=O)(c1ccc(Cl)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.70
CYP3A4 P08684 1/20 0.70
MAPK1 P28482 1/20 0.70
CYP1A2 P05177 1/20 0.65
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
HTR6 P50406 1/20 0.54
MAPT P10636 2/20 0.54
LMNA P02545 1/20 0.54
NFKB1 P19838 1/20 0.54
NFKB2 Q00653 1/20 0.54
RELA Q04206 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA9 Q16790 1/20 0.54
PTGS2 P35354 2/20 0.53
PTGS1 P23219 1/20 0.53
KDM4E B2RXH2 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1024710 0.91 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1CYP1A2KMT2A
SCHEMBL5524377 0.91 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1CYP1A2KMT2A
SCHEMBL10395087 0.91 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1CYP1A2KMT2A
SCHEMBL11590997 0.91 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1CYP1A2KMT2A
SCHEMBL11589601 0.91 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1CYP1A2KMT2A
SCHEMBL5028733 0.91 ALDH1A1 (0.84) ALDH1A1CYP3A4MAPK1CYP1A2KMT2A
SCHEMBL250144 0.89 ALDH1A1 (0.80) ALDH1A1CYP3A4MAPK1KMT2AMEN1
SCHEMBL18194389 0.89 HTR6 (0.68) ALDH1A1HTR6CA12CA1CA2
SCHEMBL9001233 0.89 HTR6 (0.68) ALDH1A1HTR6CA12CA1CA2
SCHEMBL3026340 0.86 HTR6 (0.74) ALDH1A1HTR6CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3033368-B1 PROCESS FOR MAKING POLYARYLETHERS AND USE IN MEMBRANE PREPARATION FRESENIUS MEDICAL CARE HOLDINGS INC (US) 2023-05-03 EP disclosed
CN-108299642-B Method for preparing polyarylether and use thereof in membrane preparation 费森尤斯医疗保健集团 2022-02-18 CN disclosed
CN-110088171-A The method for continuous production of continuous polymerization unit and polymer 株式会社吴羽 2019-08-02 CN disclosed
CN-109923153-A The apparatus for continuously production and method for continuous production of polymer 株式会社吴羽 2019-06-21 CN disclosed
CN-109923146-A The method for continuous production of aromatic polymer and the apparatus for continuously production of aromatic polymer 株式会社吴羽 2019-06-21 CN disclosed
EP-3033368-A1 PROCESS FOR MAKING POLYARYLETHERS AND USE IN MEMBRANE PREPARATION Fresenius Medical Care Holdings, Inc. (US) 2016-06-22 EP disclosed
US-9353220-B2 Process for making polyarylethers and use in membrane preparation FRESENIUS MEDICAL CARE HOLDINGS, INC. (US) 2016-05-31 US disclosed
CN-102924898-B Polyacryletherone, compositions, molded product and preparation thereof POLYMICS KUNSHAN CO LTD 2015-04-15 CN disclosed
WO-2015023395-A1 PROCESS FOR MAKING POLYARYLETHERS AND USE IN MEMBRANE PREPARATION FRESENIUS MEDICAL CARE HOLDINGS, INC. (US) 2015-02-19 WO disclosed
US-20150048533-A1 Process For Making Polyarylethers And Use In Membrane Preparation FRESENIUS MEDICAL CARE HOLDINGS, INC (US) 2015-02-19 US disclosed
EP-0323076-A2 Polyaryletherketones VICTREX MANUFACTURING LIMITED (GB) 1989-07-05 EP disclosed
EP-0292211-A2 Production and/or handling of polymers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-11-23 EP disclosed
US-4711945-A Polyketone IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-12-08 US disclosed
EP-0194062-A3 POLYARYLETHER IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-11-20 EP disclosed
EP-0182648-A2 Process for the Preparation of Polyetherketones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-05-28 EP disclosed
US-4331798-A Production of aromatic polyethers with infusible particulate substance IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-05-25 US disclosed
EP-0010868-A2 Production of aromatic polyethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-05-14 EP disclosed
US-4176222-A BY HEATING A BISPHENOL, DIHALOBENZENOID COMPOUND WITH SODIUM CARBONATE OR BICARBONATE AND A SECOND ALKALI METAL CARBONATE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-11-27 US disclosed
US-4128396-A Process for the improvement of dyeing properties of pigments of the anilino and arylmercapto anthraquinone series CIBA-GEIGY CORPORATION (US) 1978-12-05 US disclosed
US-4105636-A BOILING ORGANIC SULPHOXIDE OR SULPHONE SOLVENT CONTAINING MIXTURE OF BISPHENOL AND AN AROMATIC DIHALO COMPOUND OR A HALOPHENOL AND AN ALKALI CARBONATE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-08-08 US disclosed