Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | GLI1 | P08151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30128341 | 1.00 | DPP4 (0.32) | DPP4GLI1 | |
| SCHEMBL18588982 | 0.84 | DPP4 (0.33) | DPP4 | |
| SCHEMBL14504665 | 0.84 | DPP4 (0.33) | DPP4GLI1 | |
| SCHEMBL30839243 | 0.82 | DPP4 (0.34) | DPP4GLI1 | |
| SCHEMBL4760467 | 0.78 | DPP4 (0.34) | DPP4GLI1 | |
| SCHEMBL21029706 | 0.78 | GABRR1 (0.31) | — | |
| SCHEMBL13631051 | 0.78 | GABRR1 (0.31) | — | |
| SCHEMBL4109097 | 0.77 | GABRR1 (0.50) | — | |
| SCHEMBL4428766 | 0.77 | GABRR1 (0.50) | — | |
| SCHEMBL4428770 | 0.77 | GABRR1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180179226-A1 | Processes for the Preparation of Edoxaban and Intermediates Thereof | THE BANK OF NOVA SCOTIA (CA) | 2018-06-28 | — | — | US | disclosed |
| EP-2980067-B1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2017-05-17 | — | — | EP | disclosed |
| EP-2980067-B1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE DIAMINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2017-05-17 | — | — | EP | disclosed |
| EP-2589590-B1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO CO LTD (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-9447118-B2 | Preparation method of optically active diamine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-20 | — | — | US | disclosed |
| US-9447118-B2 | Preparation method of optically active diamine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-20 | — | — | US | disclosed |
| US-9447118-B2 | Preparation method of optically active diamine compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-09-20 | — | — | US | disclosed |
| EP-1925611-B1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | DAIICHI SANKYO CO LTD (JP) | 2016-04-13 | — | — | EP | disclosed |
| EP-2980067-A1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE DIAMINE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-02-03 | — | — | EP | disclosed |
| EP-2980067-A1 | PROCESSES FOR PREPARING OPTICALLY ACTIVE DIAMINE DERIVATIVES | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-02-03 | — | — | EP | disclosed |
| US-8901345-B2 | Process for preparation of optically active diamine derivative salt | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20130165657-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-06-27 | — | — | US | disclosed |
| EP-2589590-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-05-08 | — | — | EP | disclosed |
| US-8357808-B2 | Process for producing diamine derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-01-22 | — | — | US | disclosed |
| US-20120041206-A1 | PROCESS FOR PRODUCING DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-16 | — | — | US | disclosed |
| US-20120035369-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE DIAMINE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-02-09 | — | — | US | disclosed |
| EP-2407457-A1 | PROCESS FOR PRODUCING DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-01-18 | — | — | EP | disclosed |
| EP-2407450-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE DIAMINE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-20090105491-A1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1925611-A1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Daiichi Sankyo Company, Limited (JP) | 2008-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105491-A1 | OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | TFPI, F2, SERPINC1 | DPP4 330/4885GLI1 926/4885 |
| US-20120041206-A1 | PROCESS FOR PRODUCING DIAMINE DERIVATIVE | TFPI, TFPI2, DAO | DPP4 919/4885GLI1 1408/4885 |
| US-20130165657-A1 | PROCESS FOR PREPARATION OF OPTICALLY ACTIVE DIAMINE DERIVATIVE SALT | TFPI, F12, TFPI2 | DPP4 363/4885GLI1 1241/4885 |
| US-20120035369-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE DIAMINE DERIVATIVE | F12, DAO, TFPI | DPP4 2091/4885GLI1 1282/4885 |
| US-20180179226-A1 | Processes for the Preparation of Edoxaban and Intermediates Thereof | VKORC1, CYP2C9, VKORC1L1 | DPP4 2271/4885GLI1 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.