SCHEMBL1128337

SCHEMBL1128337

CC(=O)C1c2ccccc2Oc2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.66
HDAC3 O15379 1/20 0.61
HDAC4 P56524 1/20 0.61
HDAC1 Q13547 1/20 0.61
HDAC7 Q8WUI4 1/20 0.61
HDAC2 Q92769 1/20 0.61
HDAC10 Q969S8 1/20 0.61
HDAC11 Q96DB2 1/20 0.61
HDAC8 Q9BY41 1/20 0.61
HDAC6 Q9UBN7 1/20 0.61
HDAC9 Q9UKV0 1/20 0.61
HDAC5 Q9UQL6 1/20 0.61
KMT2A Q03164 5/20 0.61
MEN1 O00255 4/20 0.61
USP2 O75604 1/20 0.61
TSHR P16473 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27456766 0.83 ATM (0.70) ATMHDAC3HDAC4HDAC1HDAC7
SCHEMBL11805053 0.82 ATM (0.50) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL40617 0.81 ATM (0.68) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL30011680 0.81 ATM (0.68) ATMHDAC3HDAC4HDAC1HDAC7
SCHEMBL156372 0.81 ATM (0.68) ATMHDAC3HDAC4HDAC1HDAC7
SCHEMBL12513866 0.80 KMT2A (0.67) ATMHDAC3HDAC4HDAC1HDAC7
SCHEMBL1552414 0.79 ATM (1.00) ATMHDAC3HDAC4HDAC1HDAC7
SCHEMBL4777998 0.79 ATM (0.66) ATMHDAC3HDAC4HDAC1HDAC7
SCHEMBL29857778 0.79 ATM (1.00) ATMHDAC3HDAC4HDAC1HDAC7
Xanthene Carboxylic Acid SCHEMBL9551091 0.79 ATM (0.66) ATMHDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240045330-A1 NEGATIVE PHOTOSENSITIVE COMPOSITION AND PATTERN FORMATION METHOD TOKYO OHKA KOGYO CO., LTD. (JP) 2024-02-08 US disclosed
CN-117420731-A Negative photosensitive composition and pattern forming method 东京应化工业株式会社 2024-01-19 CN disclosed
CN-113286781-B Sulfonium salt, photoacid generator, curable composition, and resist composition 三亚普罗股份有限公司 2023-08-08 CN disclosed
US-20230236505-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, AND LAMINATED FILM SAN-APRO LTD. (JP) 2023-07-27 US disclosed
CN-116018558-A Negative photosensitive resin composition, pattern forming method and laminated film 三亚普罗股份有限公司 2023-04-25 CN disclosed
EP-3909943-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION AND RESIST COMPOSITION San-Apro Ltd. (JP) 2021-11-17 EP disclosed
WO-2020145043-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION AND RESIST COMPOSITION サンアプロ株式会社 2020-07-16 WO disclosed
EP-2284165-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION SAN APRO LTD (JP) 2013-02-20 EP disclosed
US-8278030-B2 Sulfonium salt, photoacid generator, and photocurable composition and cured body thereof SAN-APRO LIMITED (JP) 2012-10-02 US disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed
US-20100305152-A1 METHOD OF INHIBITING THE GROWTH OF HELICOBACTER PYLORI NATIONAL TSING HUA UNIVERSITY (TW) 2010-12-02 US disclosed
US-20100160255-A1 SPIRO-CYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-06-24 US disclosed
US-20100160255-A1 SPIRO-CYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-06-24 US disclosed
EP-1911753-A1 SPIRO-CYCLIC COMPOUND Takeda Pharmaceutical Company Limited (JP) 2008-04-16 EP disclosed
EP-0819121-B1 TRICYCLIC COMPOUNDS USEFUL FOR INHIBITION OF G-PROTEIN FUNCTION AND FOR TREATMENT OF PROLIFERATIVE DISEASES SCHERING CORP (US) 2007-05-30 EP disclosed
EP-1114043-B1 NAPHTHOPYRANS ANNELATED IN C 6?-C 7?, THEIR PREPARATION AND COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM CORNING INC (US) 2003-03-26 EP disclosed
EP-1114043-A1 NAPHTHOPYRANS ANNELATED IN C 6?-C 7?, THEIR PREPARATION AND COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM CORNING INCORPORATED (US) 2001-07-11 EP disclosed
US-6207084-B1 PHOTOCHROMIC COMPOSITIONS AND PHOTOCHROMIC OPHTHALMIC ARTICLES (LENSES FOR EXAMPLE) WHICH CONTAIN SAID NAPHTHOPYRANS CORNING S.A. (FR) 2001-03-27 US disclosed
WO-2000015631-A1 NAPHTHOPYRANS ANNELATED IN C6-C7, THEIR PREPARATION AND COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THEM CORNING INCORPORATED (US) 2000-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100305152-A1 METHOD OF INHIBITING THE GROWTH OF HELICOBACTER PYLORI HPD, HAAO, HK1 ATM 2162/4885HDAC3 1759/4885HDAC4 1425/4885
US-20100160255-A1 SPIRO-CYCLIC COMPOUND ACACA, CPT1B, PC ATM 630/4885HDAC3 290/4885HDAC4 536/4885
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF ARSA, ASIC1, TST ATM 928/4885HDAC3 1230/4885HDAC4 1247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.