Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.67 |
| ▸ | APAF1 | O14727 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.67 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.67 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.66 |
| ▸ | MMP2 | P08253 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.66 |
| ▸ | CNR1 | P21554 | 1/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299039 | 1.00 | TDP1 (0.67) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL5493473 | 1.00 | TDP1 (0.67) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4132476 | 1.00 | TDP1 (0.67) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL3299820 | 0.94 | TDP1 (0.67) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4124260 | 0.94 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4627402 | 0.94 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL5494777 | 0.94 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4141299 | 0.94 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10401059 | 0.94 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL4141307 | 0.94 | TDP1 (0.75) | TDP1APAF1LMNATSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741478-B2 | Salts in the preparation of cephalosporin antibiotics | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2010-06-22 | — | — | US | disclosed |
| US-20080306256-A1 | Salts in the Preparation of Cephalosporin Antibiodies | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2008-12-11 | — | — | US | disclosed |
| EP-1765833-A2 | NEWS SALTS IN THE PREPARATION OF CEPHALOSPORIN ANTIBIOTICS | Orchid Chemicals and Pharmaceuticals Limited (IN) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006006040-A2 | NEWS DIAMINE SALTS OF CEPHALOSPORIN ANTIBIOTICS AND THEIR PREPARATION | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2006-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306256-A1 | Salts in the Preparation of Cephalosporin Antibiodies | ABCB11, SLC10A1, NISCH | TDP1 4358/4885APAF1 4262/4885LMNA 4024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.