Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814784 | 0.93 | OPRM1 (0.38) | L3MBTL1OPRM1P2RX7 | |
| SCHEMBL3308257 | 0.91 | L3MBTL1 (0.34) | L3MBTL1OPRM1P2RX7 | |
| SCHEMBL3306666 | 0.85 | OPRM1 (0.36) | ADORA1OPRM1P2RX7 | |
| SCHEMBL1818958 | 0.84 | SCN9A (0.37) | L3MBTL1HDAC9 | |
| SCHEMBL1815542 | 0.82 | HDAC9 (0.33) | L3MBTL1HDAC9 | |
| SCHEMBL3299180 | 0.82 | HTT (0.40) | L3MBTL1NR3C2HDAC9DGAT1 | |
| SCHEMBL3261317 | 0.81 | NTRK1 (0.38) | P2RX7 | |
| SCHEMBL1814343 | 0.81 | NR1H4 (0.33) | L3MBTL1P2RX7 | |
| SCHEMBL3303524 | 0.80 | ADORA1 (0.51) | NR3C2ADORA1OPRM1 | |
| SCHEMBL1816105 | 0.74 | KDM4E (0.44) | L3MBTL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099681-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099681-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | CYP3A5, ABAT, TPMT | L3MBTL1 2170/4885NR3C2 1557/4885HDAC9 1882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.