Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MDH1 | P40925 | 7/20 | 0.35 |
| ▸ | MDH2 | P40926 | 7/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | APAF1 | O14727 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297583 | 0.82 | SHBG (0.41) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL3298666 | 0.78 | SHBG (0.39) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL3294498 | 0.76 | TSHR (0.46) | SMN1; SMN2MAPTLMNAALDH1A1TSHR | |
| SCHEMBL3294314 | 0.76 | SHBG (0.32) | SHBGCYP3A4SMN1; SMN2 | |
| SCHEMBL3299388 | 0.74 | CNR2 (0.50) | CNR1 | |
| SCHEMBL10515698 | 0.73 | SHBG (0.67) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL3294363 | 0.73 | CYP3A4 (0.31) | CYP3A4SMN1; SMN2 | |
| SCHEMBL3303307 | 0.73 | SHBG (0.46) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL3297694 | 0.73 | SHBG (0.46) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 | |
| SCHEMBL28747587 | 0.72 | CYP3A4 (0.61) | SHBGCYP3A4SMN1; SMN2MDH1MDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741393-B2 | Organic silicon-based compound and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-22 | — | — | US | disclosed |
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | ARSA, OR10J3, HDAC10 | SHBG 2999/4885CYP3A4 1577/4885SMN1; SMN2 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.