SCHEMBL3300236

SCHEMBL3300236

CCCCc1cc(CCCC)c([SiH](O[SiH](c2cc(CCCC)c(CCCC)cc2CCCC)c2cc(CCCC)c(CCCC)cc2CCCC)c2cc(CCCC)c(CCCC)cc2CCCC)cc1CCCC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.36
ALOX5 P09917 5/20 0.35
PTGS2 P35354 3/20 0.34
TLR8 Q9NR97 2/20 0.34
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
HTT P42858 2/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPT P10636 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NPC1 O15118 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3298127 0.78 SKP2 (0.42) PTGS2TLR8ESR1HTTMEN1
SCHEMBL3298632 0.78 SKP2 (0.42) TYRPTGS2TLR8ESR1HTT
SCHEMBL11682168 0.78 TYR (0.50) TYRALOX5PTGS2TLR8HTT
SCHEMBL3293244 0.74 LIPG (0.42) TYRALOX5PTGS2TLR8CYP3A4
SCHEMBL3300290 0.74 GRIN2D (0.33) ALOX15
SCHEMBL3297018 0.73 TYR (0.42) TYRALOX5PTGS2TLR8HTT
SCHEMBL3296177 0.73 MAPK1 (0.44) TYRALOX5PTGS2TLR8HTT
SCHEMBL27572760 0.73 TYR (0.46) TYRALOX5PTGS2TLR8HTT
SCHEMBL3295522 0.72 TYR (0.37) TYRALOX5TLR8HTTMEN1
SCHEMBL3298696 0.71 NPC1 (0.41) TYRALOX5PTGS2TLR8HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7741393-B2 Organic silicon-based compound and method of producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-22 US disclosed
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same SUMITOMO CHEMICAL COMPANY, LIMITED 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203275-A1 Organic Silicon-Based Compound And Method Of Producing The Same ARSA, OR10J3, HDAC10 TYR 43/4885ALOX5 1609/4885PTGS2 4394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.