Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3299380 | 0.84 | PTGS2 (0.38) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL245188 | 0.81 | LIPG (0.56) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29520482 | 0.81 | LIPG (0.56) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13714249 | 0.80 | LIPG (0.44) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3302642 | 0.79 | GABRA1 (0.39) | CYP2D6CYP4F2CYP4A11 | |
| SCHEMBL3482639 | 0.79 | LIPG (0.41) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Benzene SCHEMBL3118223 | 0.79 | LIPG (0.54) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2049761 | 0.79 | LIPG (0.54) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| Ammonia Solution, Strong SCHEMBL28991000 | 0.79 | LIPG (0.54) | LIPGTLR8CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29414141 | 0.79 | LIPG (0.54) | LIPGTLR8CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741393-B2 | Organic silicon-based compound and method of producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-22 | — | — | US | disclosed |
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203275-A1 | Organic Silicon-Based Compound And Method Of Producing The Same | ARSA, OR10J3, HDAC10 | LIPG 4236/4885TLR8 2951/4885CYP3A4 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.