Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.64 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.64 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.64 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.64 |
| ▸ | TDP2 | O95551 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26983156 | 0.99 | MEN1 (0.62) | MEN1KMT2ATIMP3HPSERECQL | |
| SCHEMBL11465116 | 0.97 | MEN1 (0.68) | MEN1KMT2ATIMP3HPSERECQL | |
| SCHEMBL11413353 | 0.91 | TIMP3 (0.59) | MEN1KMT2ATIMP3HPSERECQL | |
| SCHEMBL11426635 | 0.90 | TIMP3 (0.57) | MEN1KMT2ATIMP3HPSERECQL | |
| SCHEMBL17903246 | 0.88 | TIMP3 (0.58) | MEN1KMT2ATIMP3HPSERECQL | |
| SCHEMBL11593413 | 0.87 | TIMP3 (0.66) | MEN1KMT2ATIMP3HPSERECQL | |
| SCHEMBL30205446 | 0.87 | HPGD (0.64) | MEN1KMT2ATIMP3HPSERECQL | |
| SCHEMBL11407455 | 0.87 | TIMP3 (0.67) | MEN1KMT2ATIMP3HPSERECQL | |
| SCHEMBL11512361 | 0.86 | MEN1 (0.55) | MEN1KMT2ATIMP3HPSERECQL | |
| SCHEMBL11407249 | 0.85 | P2RY11 (0.74) | MEN1KMT2AHPSERECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8530448-B2 | Compounds and methods for inhibiting selectin-mediated function | GLYCOMIMETICS, INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-20100279958-A1 | COMPOUNDS AND METHODS FOR INHIBITING SELECTIN-MEDIATED FUNCTION | GLYCOMIMETICS, INC. (US) | 2010-11-04 | — | — | US | disclosed |
| US-7741312-B2 | Compounds and methods for inhibiting selectin-mediated function | GLYCOMIMETICS, INC. (US) | 2010-06-22 | — | — | US | disclosed |
| US-20060194745-A1 | Compounds and methods for inhibiting selectin-mediated function | GLYCOMIMETICS, INC. (US) | 2006-08-31 | — | — | US | disclosed |
| EP-1685145-A2 | GLYCOMIMETIC ANTAGONISTS FOR BOTH E- AND P-SELECTINS | GlycoMimetics, Inc. (US) | 2006-08-02 | — | — | EP | disclosed |
| US-7060685-B2 | Compounds and methods for inhibiting selectin-mediated function | GLYCOMIMETICS, INC. (US) | 2006-06-13 | — | — | US | disclosed |
| US-20050187171-A1 | Glycomimetic antagonists for both E-and P-selectins | GLYCOMIMETICS, INC. (US) | 2005-08-25 | — | — | US | disclosed |
| WO-2005054264-A2 | GLYCOMIMETIC ANTAGONISTS FOR BOTH E- AND P-SELECTINS | GLYCOMIMETICS, INC. (US) | 2005-06-16 | — | — | WO | disclosed |
| EP-1534725-A2 | COMPOUNDS AND METHODS FOR INHIBITING SELECTIN-MEDIATED FUNCTION | Glycomimetics, Inc. (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20040254145-A1 | Compounds and methods for inhibiting selectin-mediated function | GLYCOMIMETICS, INC. (US) | 2004-12-16 | — | — | US | disclosed |
| WO-2003097658-A2 | COMPOUNDS AND METHODS FOR INHIBITING SELECTIN-MEDIATED FUNCTION | GLYCOMIMETICS, INC. (US) | 2003-11-27 | — | — | WO | disclosed |
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4180587-A | Ureylene phenylene anionic naphthalenesulfonic acids as complement inhibitors | AMERICAN CYANAMID COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194745-A1 | Compounds and methods for inhibiting selectin-mediated function | SELE, SELL, SELP | MEN1 3282/4885KMT2A 2401/4885TIMP3 715/4885 |
| US-20050187171-A1 | Glycomimetic antagonists for both E-and P-selectins | SELE, SELP, SELPLG | MEN1 3851/4885KMT2A 2775/4885TIMP3 1240/4885 |
| US-20040254145-A1 | Compounds and methods for inhibiting selectin-mediated function | SELE, SELL, SELP | MEN1 3315/4885KMT2A 2423/4885TIMP3 709/4885 |
| US-20100279958-A1 | COMPOUNDS AND METHODS FOR INHIBITING SELECTIN-MEDIATED FUNCTION | SELE, SELL, SELP | MEN1 3315/4885KMT2A 2423/4885TIMP3 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.