Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.88 |
| ▸ | RECQL | P46063 | 2/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.69 |
| ▸ | CDK2 | P24941 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29264659 | 1.00 | TSHR (0.88) | TSHRRECQLCYP1A2CDK2CYP3A4 | |
| SCHEMBL29412055 | 0.94 | TSHR (1.00) | TSHRRECQLCYP1A2CDK2CYP3A4 | |
| SCHEMBL1944933 | 0.94 | TSHR (1.00) | TSHRRECQLCYP1A2CDK2CYP3A4 | |
| SCHEMBL29350488 | 0.94 | TSHR (1.00) | TSHRRECQLCYP1A2CDK2CYP3A4 | |
| SCHEMBL49690 | 0.94 | TSHR (1.00) | TSHRRECQLCYP1A2CDK2CYP3A4 | |
| SCHEMBL25176316 | 0.94 | TSHR (1.00) | TSHRRECQLCYP1A2CDK2CYP3A4 | |
| Hydrochloric Acid SCHEMBL584649 | 0.93 | TSHR (0.97) | TSHRRECQLCYP1A2CDK2CYP3A4 | |
| Hydrochloric Acid SCHEMBL27865862 | 0.93 | TSHR (0.97) | TSHRRECQLCYP1A2CDK2CYP3A4 | |
| Alcohol SCHEMBL28719125 | 0.91 | TSHR (0.95) | TSHRRECQLCYP1A2CDK2CYP3A4 | |
| SCHEMBL30320043 | 0.91 | TSHR (0.88) | TSHRRECQLCYP1A2CDK2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7741548-B2 | Method and composition for increasing branching and flowering response in plants | UNIVERSITY OF CONNECTICUT (US) | 2010-06-22 | — | — | US | disclosed |
| US-20070083948-A1 | Method and composition for increasing branching and flowering response in plants | UNIVERSITY OF CONNECTICUT | 2007-04-12 | — | — | US | disclosed |
| EP-0248984-A2 | Production of cytokinins by microorganisms | THE STATE OF OREGON ACTING BY AND THROUGH THE OREGON STATEBOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 1987-12-16 | — | — | EP | disclosed |