SCHEMBL3301366

SCHEMBL3301366

COC(=O)C1C(=O)CCC(=O)C1C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
HIF1A Q16665 1/20 0.46
ALDH1A1 P00352 2/20 0.44
BRD4 O60885 1/20 0.39
KMT2A Q03164 1/20 0.39
MMP2 P08253 1/20 0.35
ANPEP P15144 1/20 0.35
DNTT P04053 1/20 0.35
KDM4E B2RXH2 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNA4 P43681 1/20 0.34
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2597463 0.82 BRD4 (0.45) CYP1A2HIF1AALDH1A1BRD4KMT2A
SCHEMBL29807013 0.81 ALDH1A1 (0.46) CYP1A2HIF1AALDH1A1BRD4KMT2A
SCHEMBL7718731 0.81 CYP1A2 (0.43) CYP1A2HIF1AALDH1A1BRD4KMT2A
SCHEMBL8020201 0.81 CYP1A2 (0.43) CYP1A2HIF1AALDH1A1BRD4KMT2A
SCHEMBL9122696 0.81 ALDH1A1 (0.46) CYP1A2HIF1AALDH1A1BRD4KMT2A
SCHEMBL8020205 0.81 CYP1A2 (0.43) CYP1A2HIF1AALDH1A1BRD4KMT2A
SCHEMBL8813347 0.80 DNTT (0.41) ALDH1A1KMT2ADNTTHSD17B10MAPT
SCHEMBL8814944 0.80 TSHR (0.45) CYP1A2HIF1AALDH1A1KDM4EHSD17B10
SCHEMBL7199227 0.79 CYP1A2 (0.42) CYP1A2HIF1AALDH1A1BRD4KMT2A
SCHEMBL8999992 0.78 CYP1A2 (0.45) CYP1A2HIF1AALDH1A1BRD4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112094189-B Synthesis method of dimethyl succinylsuccinate 河北彩客新材料科技股份有限公司 2023-04-07 CN claimed
EP-3455298-B1 QUINACRIDONE PIGMENT AND A PROCESS FOR PREPARATION THEREOF GHARDA KEKI HORMUSJI (IN) 2022-10-26 EP claimed
CN-113217784-B Leveling device of preparation equipment of dimethyl succinylsuccinate 山东彩客东奥化学有限公司 2022-08-26 CN claimed
CN-112390717-B Preparation method of dimethyl succinylsuccinate 江苏苏御新材料科技有限公司 2022-08-09 CN claimed
CN-113623989-B Drying device for dimethyl succinyl succinate 河北彩客新材料科技股份有限公司 2022-07-15 CN claimed
CN-114751837-A Preparation method of intermediate 2, 5-diarylamine-terephthalic acid 唐继勇 2022-07-15 CN claimed
CN-112679330-B Hydrolysis process of dimethyl succinylsuccinate 西安向阳航天材料股份有限公司 2022-07-05 CN claimed
CN-215353430-U Dimethyl succinylsuccinate production reaction kettle with automatic cleaning device 彩客化学(沧州)有限公司 2021-12-31 CN claimed
CN-113623989-A Drying device for dimethyl succinyl succinate 彩客化学(沧州)有限公司 2021-11-09 CN claimed
CN-113600112-A Preparation method and device of 2, 5-di (p-toluidine) terephthalic acid 彩客化学(沧州)有限公司 2021-11-05 CN claimed
CN-112592272-A Environment-friendly production method for greatly reducing sewage discharge of dimethyl succinyl succinate 淄博鸿润新材料有限公司 2021-04-02 CN claimed
CN-112390717-A Preparation method of dimethyl succinylsuccinate 江苏苏御新材料科技有限公司 2021-02-23 CN claimed
CN-112094189-A Synthesis method of dimethyl succinylsuccinate 彩客化学(沧州)有限公司 2020-12-18 CN claimed
CN-111848431-A Preparation method of quinacridone intermediate 河北彩客化学股份有限公司 2020-10-30 CN claimed
CN-110642715-A Continuous preparation process of dimethyl succinylsuccinate 江苏盛世伟业新材料有限公司 2020-01-03 CN claimed
CN-209828619-U Post-treatment device for dimethyl succinylsuccinate 淄博鸿润新材料有限公司 2019-12-24 CN claimed
EP-0648733-B1 Process for the preparation of intermediates in the quinacridone synthesis CHEMIE LINZ GMBH (AT) 1998-01-21 EP claimed
US-5659076-A Process for the production of 2,5-dianilino-terephthalic acids DSM CHEMIE LINZ GMBH (AT) 1997-08-19 US claimed
US-5491255-A Process for the transesterification of dimethyl succinylsuccinate CHEMIE LINZ GMBH (AT) 1996-02-13 US claimed
US-5028643-A Perylene pigments made by condensing 2-aminobenzophenone and a dialkyl succinylsuccinate followed by cyclization, colorfastness CIBA-GEIGY CORPORATION (US) 1991-07-02 US claimed