Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718731 | 1.00 | CYP1A2 (0.43) | CYP1A2HIF1ACHRM2CHRM4CHRM3 | |
| SCHEMBL8020205 | 1.00 | CYP1A2 (0.43) | CYP1A2HIF1ACHRM2CHRM4CHRM3 | |
| SCHEMBL7199227 | 0.90 | CYP1A2 (0.42) | CYP1A2HIF1ACHRM2CHRM4CHRM3 | |
| SCHEMBL3974808 | 0.89 | CYP1A2 (0.41) | CYP1A2HIF1ACHRM2CHRM4CHRM3 | |
| SCHEMBL8999992 | 0.89 | CYP1A2 (0.45) | CYP1A2HIF1ACHRM2CHRM4CHRM3 | |
| SCHEMBL8999987 | 0.89 | CYP1A2 (0.45) | CYP1A2HIF1ACHRM2CHRM4CHRM3 | |
| SCHEMBL9000000 | 0.89 | CYP1A2 (0.45) | CYP1A2HIF1ACHRM2CHRM4CHRM3 | |
| SCHEMBL10951734 | 0.81 | ALDH1A1 (0.35) | CYP1A2HIF1ACHRM2CHRM4CHRM3 | |
| SCHEMBL3301366 | 0.81 | CYP1A2 (0.46) | CYP1A2HIF1AALDH1A1BRD4KMT2A | |
| SCHEMBL5215776 | 0.80 | CHRM2 (0.40) | CYP1A2HIF1ACHRM2CHRM4CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125556-A | Synthesis of 11-deoxyprostaglandins | THE DOW CHEMICAL COMPANY (US) | 1978-11-14 | — | — | US | claimed |
| US-6114364-A | 2-((SUBSTITUTED)ALKYL(THIO, SULFONYL, OR SULFOXY)METHYL), 3-(CARBOXYL OR ALIPHATIC HYDROCARBONYL)CYCLOPENTAN-1-ONE DERIVATIVES, EXCEPT CYSTACYCLIN; USE AS NEURON DIFFERENTIATION ACCELERATOR | NIPPON KAYAKU CO., LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0976709-A1 | 2,3-DISUBSTITUTED CYCLOPENTANONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF | NIPPON KAYAKU CO., LTD. (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-4532081-A | 2-(6'-cyano-2'-hexynyl)-2-(b,b,b -trichlorocarboethoxy)-3-carbomethoxy cyclopentanone | THE DOW CHEMICAL COMPANY (US) | 1985-07-30 | — | — | US | disclosed |
| US-4532081-A | 2-(6'-cyano-2'-hexynyl)-2-(b,b,b -trichlorocarboethoxy)-3-carbomethoxy cyclopentanone | THE DOW CHEMICAL COMPANY (US) | 1985-07-30 | — | — | US | disclosed |
| US-4447636-A | TRANS-2-B,B,B-TRICHLOROCARBOETHOXY-3 -CARBOMETHOXYCYCLOPENTANONE INTERMEDIATE | THE DOW CHEMICAL COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4447636-A | TRANS-2-B,B,B-TRICHLOROCARBOETHOXY-3 -CARBOMETHOXYCYCLOPENTANONE INTERMEDIATE | THE DOW CHEMICAL COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4146553-A | Intermediates for synthesizing 11-deoxyprostaglandins | THE DOW CHEMICAL COMPANY (US) | 1979-03-27 | — | — | US | disclosed |
| US-4146553-A | Intermediates for synthesizing 11-deoxyprostaglandins | THE DOW CHEMICAL COMPANY (US) | 1979-03-27 | — | — | US | disclosed |
| US-4125556-A | Synthesis of 11-deoxyprostaglandins | THE DOW CHEMICAL COMPANY (US) | 1978-11-14 | — | — | US | disclosed |
| US-4125556-A | Synthesis of 11-deoxyprostaglandins | THE DOW CHEMICAL COMPANY (US) | 1978-11-14 | — | — | US | disclosed |